Reactive oxygen species (ROS) are radical and non-radical oxygen species produced by the partial reduction of oxygen, including superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•). Endogenous ROS are produced by cells during their normal oxidative metabolism in the mitochondria as well as when they react to xenobiotics, cytokines, and bacterial invasion.
By directly inhibiting MAPK phosphatases, ROS also activates MAPK pathways. Through PTEN, ROS produced by growth factor stimulation are capable of reversibly controlling the redox state of the PI3K pathway. The cellular response to ROS may involve the activation of autophagy.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V72941 | (+)-Schisandrin B ((+)-Schisandrin B) | 82467-52-5 | (+)-Schisandrin B is an enantiomer of Schisandrin B. |
|
V72973 | (-)-Lyoniresinol 9'-O-glucoside | 143236-02-6 | (-)-Lyoniresinol 9'-O-glucoside is an inhibitor (blocker/antagonist) of ROS. |
|
V67649 | (E/Z)-GSK5182 | 2699724-40-6 | (E/Z)-GSK5182 is the racemate of (E)-GSK5182 and (Z)-GSK5182. |
|
V72906 | (±)-Carnitine-d9 chloride (DL-Carnitine-d9 (chloride)) | 1219386-75-0 | (±)-Carnitine-d9 (chloride) is the deuterated form of (±)-Carnitine chloride. |
|
V72939 | (±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) | 69097-97-8 | (±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) was extracted from Angelica keiskei, a cold-resistant perennial herb of the Apiaceae family. |
|
V67090 | 1,3-Diphenylisobenzofuran (DPBF) | 5471-63-6 | 1,3-Diphenylisobenzofuran (DPBF) is used as a selective probe for the detection and quantification of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). |
|
V72945 | 2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside | 1447969-66-5 | 2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside compound in Lilium brownie var. |
|
V72921 | 2,4,7-Trihydroxy-9,10-dihydrophenanthrene | 70205-52-6 | 2,4,7-Trihydroxy-9,10-dihydrophenanthrene is a dihydrophenanthrene analogue that can be found in Pholidota chinensis Lindl. |
|
V72904 | 2-Selenouracil | 16724-03-1 | 2-Selenouracil is an effective photosensitizer used in photodynamic therapy. |
|
V72965 | 3′-Hydroxy-4′-O-methylglabridin | 175554-11-7 | 3′-Hydroxy-4′-O-methylglabridin is an antioxidant that effectively prevents NADH-dependent peroxidation. |
|
V72896 | 3-Demethylcolchicine | 7336-33-6 | 3-Demethylcolchicine is a metabolite of colchicine. |
|
V72955 | 4-Methyl-6-phenyl-2H-pyranone | 4467-30-5 | 4-Methyl-6-phenyl-2H-pyranone may be utilized to prepare N-hydroxypyridone analogues that protect astrocytes from hydrogen peroxide-induced toxicity by improving mitochondrial function. |
|
V72910 | 5-Hydroxyoxindole | 3416-18-0 | 5-Hydroxyoxindole is a structural analog of uric acid. |
|
V72954 | 6-Deoxyjacareubin | 16265-56-8 | 6-Deoxyjacareubin is a natural xanthone extracted from the leaves of Vismia latifolia. |
|
V69158 | 8α-Tigloyloxyhirsutinolide 13-O-acetate (8αTGH) | 83182-58-5 | 8α-Tigloyloxyhirsutinolide 13-O-acetate (8αTGH) is an orally bioavailable STAT3 inhibitor. |
|
V72967 | AHK | 126828-32-8 | AHK is a biologically active peptide with antioxidant effects and has been reported to be used as an ingredient of cosmetics. |
|
V72928 | Allyl methyl trisulfide | 34135-85-8 | Allyl methyl trisulfide is a volatile organic/chemical reagent and a component of garlic (Allium sativum L. |
|
V73391 | Aminoguanidine hemisulfate | 996-19-0 | Aminoguanidine hemisulfate is an inhibitor (blocker/antagonist) of NOS and ROS. |
|
V72947 | Anemarrhenasaponin Ia (Anemarrhenasaponin IA) | 221317-02-8 | Anemarrhenasaponin Ia can be extracted from Anemarrhenae rhizome and inhibits the further production of superoxide induced by fMLP. |
|
V77255 | Anti-inflammatory agent 38 | Anti-inflammatory agent 38 (compound 23d) is a potent Nrf2/HO-1 inhibitor (antagonist) with IC50 of 0.38 μM for NO. |
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