| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V4205 | Amicarbazone | 129909-90-6 | Amicarbazone (also known as BAY-MKH3586 and BAY314666) is a novel, potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII); Amicarbazone is a new triazolinone herbicide with a broad spectrum of weed control. |
|
V4243 | AZD6482 S-isomer | 1173900-37-2 | AZD6482 S-isomer, is an isomer of AZD6482 which is a novel, potent, selective and ATP competitive PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and is 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ in cell-free assays. |
|
V4171 | BAY-524 | 1445830-39-6 | BAY-524is a novel and potent Bub1 inhibitor with anIC50of 450 nM for human Bub1 in the presence of 2 mM ATP. |
|
V4168 | BAY-598 R-isomer | 1906920-28-2 | BAY-598 R-isomer (R-BAY598) is the R-enantiomer of BAY589 which is a peptide-competitive SMYD2 inhibitor with antineoplastic activity. |
|
V4164 | BAY-677 | 2117404-84-7 | BAY-677 is an inactive and negative control for BAY-678. |
|
V4129 | BLU-782 | 2141955-96-4 | BLU-782 has been discontinued. |
|
V4273 | Bucladesine (Dibutyryl-cAMP) | 362-74-3 | Bucladesine (DC2797; DC-2797; Dibutyryl-cAMP) is a potent and cell-permeable PKA activator and a cAMP analog that mimics the action of endogenous cAMP. |
|
V4136 | Dioctyl decanedioate | 2432-87-3 | Dioctyl decanedioate (decadioic acid, dioctyl ester; Decanedioic acid, dioctyl ester; decanedioicaciddioctylester; Dioctyl-1,10-decanedioate) is a biochemical. |
|
V4161 | Diroximel fumarate | 1577222-14-0 | Diroximel fumarate (also known as ALKS 8700) is a novel compound that is taken orally and rapidly converted into monomethyl fumarate (MMF). |
|
V4210 | Emiglitate | 80879-63-6 | Emiglitate (also known as BAY o 1248) is a novel, potent, selective and competitive inhibitor ofα-glucoside hydrolase. |
|
V4148 | Fenebrutinib (GDC-0853) HCl | 2128304-54-9 | Fenebrutinib HCl (formerly known RG-7845; GDC-0853 hydrochloride) is an orally bioavailable, and noncovalent (reversible) brutons tyrosine kinase (BTK) inhibitor (Ki = 0.91 nM) with anticancer and anti-inflammatory activity. |
|
V4137 | GSK-2336805 | 1256390-53-0 | GSK-2336805 (also known as GSK-805; GSK2336805; JNJ-56914845) is a novel and potent inhibitor of HCV NS5A. |
|
V4046 | Irosustat | 288628-05-7 | Irosustat (formerlyknown as STX64, BN83495 or 667 coumate) is a novel potent and irreversibleinhibitor of steroid sulfatasewith anIC50of 8 nM and has the potential for treating breast cancer. |
|
V4075 | LGD-4033 | 1165910-22-4 | LGD-4033 (also known as VK-5211 and Ligandrol) isa novel, potent and selective androgen receptor modulator (SARM) and is being investigated by Ligand Pharmaceuticals for treatment of conditions such as muscle wasting and osteoporosis. |
|
V4291 | MK-6240 | 1841078-87-2 | MK-6240 is a novel positron emission tomography (PET) tracer fordetecting neurofibrillary tangles (NFTs). |
|
V4015 | ML-290 | 1482500-76-4 | ML-290, a 2-acetamido-N-phenylbenzamide analog, is a novel potent, selective and orally bioactive agonist of the relaxin/insulin-like family peptide receptor (RXFP1)and an activator of anti-fibrotic genes with anEC50of 94 nM. |
|
V4010 | ML-7 | 109376-83-2 | ML-7 (ML7) is a potent Myosin light chain kinase (MLCK) inhibitor with IC50of 300 nM and IC50>10 μM for MLCK and TRPC6 channel respectively. |
|
V4023 | ML132 | 1230628-71-3 | ML132 (also known as NCGC 00185682) is a potent and selectivecaspase 1inhibitor with anIC50of 0.316 nM. |
|
V4225 | NSC 77674 | 737-86-0 | NSC77674 (also known as PIH or Pyridoxal isonicotinoyl hydrazone) is is a novel, potent, lipophilic, nontoxic, iron-chelating agent that shows high iron chelation efficacy both in vitro in cell culture models and in vivo in rats and mice. |
|
V4132 | PROTAC-VHL-ligand | 1448297-52-6 | PROTAC-VHL-ligand or Protein degrader 1 is a novel and potent small molecule ligand forVHL (Von Hippel-Lindau), anE3 ligasewhich has been targeted by many PROTACs (proteolysis-targeting chimeras) degarders. |
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