The cell-surface serine protease known as fibroblast activation protein (FAP) affects different hormones and elements of the extracellular matrix. FAP is frequently used as a marker for pro-tumorigenic stroma and is highly upregulated in a variety of cancers.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V79388 | FAP-IN-1 | FAP-IN-1 is a fibroblast activation protein (FAP) inhibitor (antagonist) with IC50 of 3.3 nM. | ||
V74897 | FAP-IN-2 | 2471983-20-5 | FAP-IN-2 is an analogue of 99mTc-labeled isonitrile-containing fibroblast activation protein (FAPI) inhibitor that can be used for tumor imaging. | |
V77022 | FAP-IN-2 TFA | FAP-IN-2 TFA is an analogue of 99mTc-labeled isonitrile-containing FAP inhibitor that can be used for tumor imaging. | ||
V74893 | FAPI-2 | 2370952-98-8 | FAPI-2 is a fibroblast activation protein (FAP) inhibitor that has applications in cancer-related research. | |
V77023 | FAPI-2 TFA | FAPI-2 TFA is a fibroblast activation protein (FAP) inhibitor (antagonist) with potential use in cancer-related research. | ||
V74894 | FAPI-34 | 2374782-07-5 | FAPI-34 is a fibroblast activating protein (FAP) inhibitor (antagonist) with good pharmacokinetic and biochemical properties, disclosed in patent WO2019154886A1. | |
V51734 | FAPI-46 | 2374782-04-2 | FAPI-46 is a quinoline-based activator of fibroblast-activated protein (FAP). | |
V74898 | FAPI-74 | 2374782-76-8 | FAPI-74 is a PET (positron emission tomography) tracer for fibroblast activating protein. | |
V74895 | Fluorogen binding modulator-1 | 510716-65-1 | Fluorogen binding modulator-1 (PubChem SID 125240934) is a fluorescein-activated protein (FAP)-fluorogen binding modulator with a -log EC50 of 6.61 for AM2.2-β2AR and AM2.2-gpr32 respectively. | |
V76701 | NH2-UAMC1110 TFA | NH2-UAMC1110 TFA is a UAMC1110 analogue that may be utilized in the synthesis/preparation of FAPI-QS. | ||
V74891 | Sibrotuzumab (BIBH 1; Anti-Human FAP Recombinant Antibody) | 216669-97-5 | Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody (mAb) targeting fibroblast activating protein (FAP). | |
V74896 | Zilganersen (ION373) | 2305355-56-8 | Zilganersen (ION373) is an inhibitor (blocker/antagonist) of glial fibrillary acidic protein (GFAP) and is an antisense oligonucleotide. | |
V74892 | Zilganersen sodium (ION373 sodium) | 2305355-64-8 | Zilganersen sodium is an inhibitor (blocker/antagonist) of glial fibrillary acidic protein (GFAP) and may be utilized in the study of Alexander disease (AxD). |