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    Catalog No: V0040
    CAS No. (CAS Registry Number): 890090-75-2
    Description: Nutlin-3, a tetra-substituted imidazoline, is a novel potent and selective small-molecule antagonist/inhibitor of murine double minute 2 (MDM2), which occupies the binding site of p53 in ...
    Catalog No: V0041
    CAS No. (CAS Registry Number): 58131-57-0
    Description: NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase. NSC 207895 is a benzofuroxan d...
    Catalog No: V0042
    CAS No. (CAS Registry Number): 675576-98-4
    Description: Nutlin-3a, the active enantiomer of Nutlin-3, is a potent inhibitor of the p53/MDM2 (murine double minute) protein protein interaction with IC50 of 90 nM in a cell-free assay. Nutlin-3 bi...
    Catalog No: V0043
    CAS No. (CAS Registry Number): 675576-97-3
    Description: Nutlin-3b, a less active isomer of nutlin-3, is a p53/MDM2 (murine double minute 2) antagonist or inhibitor with IC50 value of 13.6 μM, it is 150-fold less potent (+)-enantiomer of Nutlin...
    Catalog No: V0044
    CAS No. (CAS Registry Number): 1364488-67-4
    Description: YH239-EE (YH239-EE; YH239EE; YH239 EE), the ethyl ester of YH239, is a novel and highly potent p53-MDM2 antagonist and an apoptosis inducer. In OCI-AML-3 cells, YH239-EE potently inh...
    Catalog No: V0045
    CAS No. (CAS Registry Number): 939981-39-2
    Description: RG7112 (also known as RO5045337) is a novel, potent and highly selective antagonist of the p53-MDM2 protein-protein interaction with IC50 of 11 nM. Restoration of p53 ...
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