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    Catalog No: V1573
    CAS No. (CAS Registry Number): 755038-02-9
    Description: BI2536 is a novel and potent small molecule dual PLK1 and BRD4 inhibitor with IC50s of 0.83 and 25 nM, respectively in a cell-free assay. BI-2536 suppresses IFNB (encoding IFN-β) gen...
    Catalog No: V1574
    CAS No. (CAS Registry Number): 755038-65-4
    Description: Volasertib (formerly also known as BI 6727) is a novel and highly potent dihydropteridinone Plk1 inhibitor with IC50 of 0.87 nM in a cell-free assay. It shows 6- and 65-fold greater selec...
    Catalog No: V1575
    CAS No. (CAS Registry Number): 1225497-78-8
    Description: Rigosertib sodium (formerly also known as ON-01910), the sodium salt of Rigosertib, is a novel, potent and non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM in a cell-free assa...
    Catalog No: V1576
    CAS No. (CAS Registry Number): 929095-18-1
    Description: GSK-461364 is a novel, potent, selective, reversible and ATP-competitive small molecule Polo-like kinase 1 (PLK1) inhibitor with a Ki value of 2.2 nM. GSK-46...
    Catalog No: V1577
    CAS No. (CAS Registry Number): 173529-46-9
    Description: HMN-214 is a potent and orally active prodrug of HMN-176, which alters the cellular spatial orientation of Plk1. HMN-214 is a stilbene derivative that interferes with the subcellular spat...
    Catalog No: V1578
    CAS No. (CAS Registry Number): 1228960-69-7
    Description: MLN0905 is a novel, potent and selective small-molecule inhibitor of PLK1 with IC50 of 2 nM. MLN0905 inhibits cell proliferation in a broad range of human tumor cells including DLBCL cell...
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