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    Catalog No: V0013
    CAS No. (CAS Registry Number): 881202-45-5
    Description: Serdemetan (formerly also named as JNJ26854165; JNJ-26854165; JNJ 26854165) is originally developed as an activator of p53, is now regarded as a novel, potent and orally bioacti...
    Catalog No: V0014
    CAS No. (CAS Registry Number): 63208-82-2
    Description: Pifithrin-α (Pifithrin-α hydrobromide) is an inhibitor of p53 which inhibits p53 protein transcription and p53-dependent transactivation of p53-responsive genes. It also ac...
    Catalog No: V0015
    CAS No. (CAS Registry Number): 213261-59-7
    Description: RITA (also known as NSC 652287) is a novel and potent inhibitor of p53-HDM-2 interaction which binds to p53dN, with a Kd of 1.5 nM, and also induces DNA-DNA cross-links. It induces b...
    Catalog No: V0016
    CAS No. (CAS Registry Number): 380315-80-0
    Description: Tenovin-1, a small molecule discovered by a cell-based screen, is a bio-active activator of p53 that elevates the levels of p53 protein, p53-downstream target p21CIP/WAF1 protein and...
    Catalog No: V0017
    CAS No. (CAS Registry Number): 71555-25-4
    Description: NSC319726 is a novel and potent p53(R175) mutant reactivator, exhibits growth inhibition in cells expressing mutant p53, with IC50 of 8 nM for p53(R175) mutant, shows no inhibition f...
    Catalog No: V0018
    CAS No. (CAS Registry Number): 803647-40-7
    Description: NSC59984 is a novel and potent p53 pathway activator that acts through induction of mutant p53 protein degradation and p73 activation. NSC59984 induces mutant p53 protein degrad...
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