| Size | Price | |
|---|---|---|
| 50mg | ||
| 500mg |
1,5-Anhydro-D-sorbitol, a cyclic polyol, is a short-term marker for glycemic control and also a metabolic product of 1,5 anhydro-D-fructose. 1,5-Anhydro-D-sorbitol is used as a reference in analytical procedures that assess the metabolism of 1,5 anhydro-D-fructose, a food supplement with potential benefits as an antioxidant, antimicrobial, and antidiabetic agent.
| ln Vitro |
1,5-Anhydrosorbitol can show that metabolite scores place people at a higher risk of developing diabetes or insulin resistance, and so coronary heart disease (CHD)[1].
|
|---|---|
| References | |
| Additional Infomation |
1,5-anhydro-D-glucitol is an anhydro sugar of D-glucitol. It has a role as a human metabolite. It is functionally related to a D-glucitol.
1,5-Anhydro-D-glucitol has been reported in Polygala tenuifolia, Medicago sativa, and other organisms with data available. |
| Molecular Formula |
C6H12O5
|
|---|---|
| Molecular Weight |
164.15648
|
| Exact Mass |
164.068
|
| CAS # |
154-58-5
|
| PubChem CID |
64960
|
| Appearance |
White to off-white solid powder
|
| Density |
1.533 g/cm3
|
| Boiling Point |
376.8ºC at 760 mmHg
|
| Melting Point |
142-143ºC
|
| Flash Point |
181.7ºC
|
| Index of Refraction |
1.581
|
| LogP |
-2.1
|
| Hydrogen Bond Donor Count |
4
|
| Hydrogen Bond Acceptor Count |
5
|
| Rotatable Bond Count |
1
|
| Heavy Atom Count |
11
|
| Complexity |
128
|
| Defined Atom Stereocenter Count |
4
|
| SMILES |
C1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
|
| InChi Key |
MPCAJMNYNOGXPB-SLPGGIOYSA-N
|
| InChi Code |
InChI=1S/C6H12O5/c7-1-4-6(10)5(9)3(8)2-11-4/h3-10H,1-2H2/t3-,4+,5+,6+/m0/s1
|
| Chemical Name |
(2R,3S,4R,5S)-2-(hydroxymethyl)oxane-3,4,5-triol
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O : ~50 mg/mL (~304.58 mM)
|
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 50 mg/mL (304.58 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 6.0916 mL | 30.4581 mL | 60.9162 mL | |
| 5 mM | 1.2183 mL | 6.0916 mL | 12.1832 mL | |
| 10 mM | 0.6092 mL | 3.0458 mL | 6.0916 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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