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500mg | ||
1g | ||
Other Sizes |
Purity: ≥98%
A 21960 is able to inhibit the synapse formation between resolvase and two directly repeated res sites, and subsequently block the site-specific recombination reaction. The Tn3-encoded resolvase protein promotes a site-specific recombination reaction between two directly repeated copies of the recombination site res. A21960 does not affect resolvase binding and bending of the DNA but inhibit synapse formation between resolvase and two directly repeated res sites.
ln Vitro |
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ln Vivo |
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Animal Protocol |
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References |
J Mol Biol.1989 Mar 20;206(2):295-304.
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Molecular Formula |
C6H9CLO3
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Molecular Weight |
164.5869
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Exact Mass |
164.024
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CAS # |
609-15-4
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Related CAS # |
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PubChem CID |
11858
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Appearance |
Typically exists as solid at room temperature
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Density |
1.2±0.1 g/cm3
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Boiling Point |
225.5±0.0 °C at 760 mmHg
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Melting Point |
-80 °C
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Flash Point |
50.0±0.0 °C
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Vapour Pressure |
0.1±0.4 mmHg at 25°C
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Index of Refraction |
1.434
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LogP |
1.66
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Hydrogen Bond Donor Count |
0
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Hydrogen Bond Acceptor Count |
3
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Rotatable Bond Count |
4
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Heavy Atom Count |
10
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Complexity |
144
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Defined Atom Stereocenter Count |
0
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SMILES |
ClC([H])(C(C([H])([H])[H])=O)C(=O)OC([H])([H])C([H])([H])[H]
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InChi Key |
RDULEYWUGKOCMR-UHFFFAOYSA-N
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InChi Code |
InChI=1S/C6H9ClO3/c1-3-10-6(9)5(7)4(2)8/h5H,3H2,1-2H3
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Chemical Name |
ethyl 2-chloro-3-oxobutanoate
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Synonyms |
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HS Tariff Code |
2934.99.9001
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
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Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Solubility (In Vitro) |
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Solubility (In Vivo) |
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Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 6.0757 mL | 30.3785 mL | 60.7570 mL | |
5 mM | 1.2151 mL | 6.0757 mL | 12.1514 mL | |
10 mM | 0.6076 mL | 3.0379 mL | 6.0757 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.