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| 500mg | ||
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| Other Sizes |
Purity: ≥98%
A-269A (also referred to as A269A) is a streptothricin-like antibiotic that was isolated from the culture broth of Streptomyces sp., strain No. A-269. The structure of the antibiotic was examined by 1H NMR, 13C NMR and fast atom bombardment mass spectra studies. Based on the spectroscopic data, A-269A was assumed to be a mixture of antibiotic LL-BL 136 and an isomeric compound in which the carbamoyl group is substituted on C-12' hydroxyl instead of C-10 hydroxyl.
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| ln Vivo |
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| Animal Protocol |
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| References |
J Antibiot (Tokyo).1987 Dec;40(12):1698-706.
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| Molecular Formula |
C17H29N7O8
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|---|---|---|
| Molecular Weight |
459.454263448715
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| Exact Mass |
459.208
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| CAS # |
38621-52-2
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| Related CAS # |
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| PubChem CID |
197178
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| Appearance |
Typically exists as solid at room temperature
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| Density |
1.86g/cm3
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| Index of Refraction |
1.764
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| LogP |
-5.1
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| Hydrogen Bond Donor Count |
8
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| Hydrogen Bond Acceptor Count |
10
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| Rotatable Bond Count |
8
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| Heavy Atom Count |
32
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| Complexity |
767
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| Defined Atom Stereocenter Count |
0
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| SMILES |
O1C(CO)C(C(C(C1NC1=NC2C(NCC(C2N1)O)=O)N(C(CNC)=O)C)O)OC(N)=O
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| InChi Key |
UVPMSKRAZBXYRJ-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C17H29N7O8/c1-19-4-8(27)24(2)11-12(28)13(32-16(18)30)7(5-25)31-15(11)23-17-21-9-6(26)3-20-14(29)10(9)22-17/h6-7,9-13,15,19,25-26,28H,3-5H2,1-2H3,(H2,18,30)(H,20,29)(H2,21,22,23)
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| Chemical Name |
[4-hydroxy-2-(hydroxymethyl)-6-[(7-hydroxy-4-oxo-1,3a,5,6,7,7a-hexahydroimidazo[4,5-c]pyridin-2-yl)amino]-5-[methyl-[2-(methylamino)acetyl]amino]oxan-3-yl] carbamate
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| Synonyms |
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
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| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
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| Solubility (In Vivo) |
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| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.1765 mL | 10.8826 mL | 21.7652 mL | |
| 5 mM | 0.4353 mL | 2.1765 mL | 4.3530 mL | |
| 10 mM | 0.2177 mL | 1.0883 mL | 2.1765 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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