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    BP897
    BP897

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    This product is for research use only, not for human use. We do not sell to patients.
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    InvivoChem Cat #: V3385
    CAS #: 314776-92-6 Purity ≥98%

    Description: BP 897 is a first potent and selective agonist of dopamine D3 receptor, and a weak antagonist of dopamine D2 receptor with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. It shows low affinities at D1 and D4 receptors with Ki values of 3 and 0.3 µM, respectively. BP 897 is a partial agonist in vitro and acts in vivo as either an agonist or an antagonist. BP 897 inhibits cocaine-seeking behaviour that depends upon the presentation of drug-associated cues, without having any intrinsic, primary rewarding effects. The data indicate that compounds like BP 897 could be used for reducing the drug craving and vulnerability to relapse that are elicited by drug-associated environmental stimuli.

    References:  1999 Jul 22;400(6742):371-5. 

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    BP897

    Name: BP-897
    CAS#: 314776-92-6
    Chemical Formula: C26H31N3O2
    Exact Mass: 417.2416
    Molecular Weight: 417.553
    Elemental Analysis: C, 74.79; H, 7.48; N, 10.06; O, 7.66
    Storage-20℃ for 3 years in powder form
    -80℃ for 2 years in solvent
    Technical InformationSynonym: BP897; BP-897; BP 897
    Chemical Name: N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide
    InChi Key: MNHDKMDLOJSCGN-UHFFFAOYSA-N
    InChi Code: InChI=1S/C26H31N3O2/c1-31-25-11-5-4-10-24(25)29-18-16-28(17-19-29)15-7-6-14-27-26(30)23-13-12-21-8-2-3-9-22(21)20-23/h2-5,8-13,20H,6-7,14-19H2,1H3,(H,27,30)
    SMILES Code: O=C(NCCCCN1CCN(C2=CC=CC=C2OC)CC1)C3=CC=C4C=CC=CC4=C3


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