| Size | Price | Stock | Qty |
|---|---|---|---|
| 100mg |
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| Other Sizes |
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| ln Vivo |
In male W rats treated with 500 or 1,000 ppm N-ethyl-N-hydroxyethylnitrosamine, subcutaneous injection of DL-serine increased the number and size of tubular cell tumors [2].
|
|---|---|
| References | |
| Additional Infomation |
Serine is an alpha-amino acid that is alanine substituted at position 3 by a hydroxy group. It has a role as a fundamental metabolite. It is an alpha-amino acid and a polar amino acid. It contains a hydroxymethyl group. It is a conjugate base of a serinium. It is a conjugate acid of a serinate. It is a tautomer of a serine zwitterion.
DL-Serine has been reported in Drosophila melanogaster, Populus tremula, and other organisms with data available. See also: Serine (annotation moved to). |
| Molecular Formula |
C3H7NO3
|
|---|---|
| Molecular Weight |
105.09258
|
| Exact Mass |
105.042
|
| CAS # |
302-84-1
|
| Related CAS # |
DL-Serine-2,3,3-d3;70094-78-9
|
| PubChem CID |
617
|
| Appearance |
White to off-white solid powder
|
| Density |
1.4±0.1 g/cm3
|
| Boiling Point |
394.8±32.0 °C at 760 mmHg
|
| Melting Point |
240ºC (dec.)
|
| Flash Point |
192.6±25.1 °C
|
| Vapour Pressure |
0.0±2.1 mmHg at 25°C
|
| Index of Refraction |
1.519
|
| LogP |
-1.58
|
| Hydrogen Bond Donor Count |
3
|
| Hydrogen Bond Acceptor Count |
4
|
| Rotatable Bond Count |
2
|
| Heavy Atom Count |
7
|
| Complexity |
72.6
|
| Defined Atom Stereocenter Count |
0
|
| InChi Key |
MTCFGRXMJLQNBG-UHFFFAOYSA-N
|
| InChi Code |
InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)
|
| Chemical Name |
2-amino-3-hydroxypropanoic acid
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
H2O : ~33.33 mg/mL (~317.16 mM)
DMSO :< 1 mg/mL |
|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 25 mg/mL (237.89 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 9.5157 mL | 47.5783 mL | 95.1565 mL | |
| 5 mM | 1.9031 mL | 9.5157 mL | 19.0313 mL | |
| 10 mM | 0.9516 mL | 4.7578 mL | 9.5157 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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