| Size | Price | Stock | Qty |
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Glyceryl monooleate is a biodegradable/biocompatible, non-toxic and lipophilic glycerol fatty acid ester for treatment of otitis externa. It can also be used as an emulsifier and an absorption enhancer in combination with bile salts, as well as in drug delivery systems and siRNA delivery.
| References | |
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| Additional Infomation |
1-oleoylglycerol is a 1-monoglyceride where the acyl group is oleoyl. It has a role as a plant metabolite. It is a 1-acylglycerol 18:1 and a monooleoylglycerol. It is functionally related to an oleic acid.
Glyceryl monooleate has been reported in Nelumbo nucifera and Saposhnikovia divaricata with data available. |
| Molecular Formula |
C21H40O4
|
|---|---|
| Molecular Weight |
356.55
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| Exact Mass |
356.292
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| CAS # |
25496-72-4
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| PubChem CID |
5283468
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| Appearance |
PLATES FROM ETHANOL
YELLOW OIL OR SOFT SOLID |
| Density |
1.0±0.1 g/cm3
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| Boiling Point |
483.3±35.0 °C at 760 mmHg
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| Melting Point |
36 - 40ºC
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| Flash Point |
155.4±19.4 °C
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| Vapour Pressure |
0.0±2.8 mmHg at 25°C
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| Index of Refraction |
1.479
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| LogP |
6.71
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| Hydrogen Bond Donor Count |
2
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| Hydrogen Bond Acceptor Count |
4
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| Rotatable Bond Count |
19
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| Heavy Atom Count |
25
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| Complexity |
315
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| Defined Atom Stereocenter Count |
0
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| SMILES |
O(C(=O)CCCCCCC/C=C\CCCCCCCC)CC(CO)O
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| InChi Key |
RZRNAYUHWVFMIP-KTKRTIGZSA-N
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| InChi Code |
InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
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| Chemical Name |
2,3-dihydroxypropyl (Z)-octadec-9-enoate
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| Synonyms |
Glyceryl monooleate; Monooleoylglycerol; Aldo 40; Emasol MO 50; Emcol O; Aldo MO; Aldo MO-FG; Monoolein; (Z)-9-Octadecenoic Acid Monoester with 1,2,3-Propanetriol; Crossential GMO; Dimodan GMO 90; Dimodan LSQK; Dremulse; Dur-Em 114; Dur-Em 204; EAR 300; Edenor GMO; Emalsy MO; Emalsy OL; Alkamuls GMO 45LG; Agnique GMO; Ajax GMO; Arlacel 129; Atmer 1007; Atsurf 595; Canamex Glicepol 182; Capmul GMO 50; ; Emalsy OL 100; Emalsy OL 100H; Emasol MO; Emerest 2400; Emerest 2421; Emrite 6009; EmuldanOlein, mono- (6CI,8CI); A 300; A 300 (ester); Adchem GMO;
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
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|---|---|
| Solubility (In Vivo) |
Note: Listed below are some common formulations that may be used to formulate products with low water solubility (e.g. < 1 mg/mL), you may test these formulations using a minute amount of products to avoid loss of samples.
Injection Formulations
Injection Formulation 1: DMSO : Tween 80： Saline = 10 : 5 : 85 (i.e. 100 μL DMSO stock solution → 50 μL Tween 80 → 850 μL Saline)(e.g. IP/IV/IM/SC) *Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH ₂ O to obtain a clear solution. Injection Formulation 2: DMSO : PEG300 ：Tween 80 : Saline = 10 : 40 : 5 : 45 (i.e. 100 μL DMSO → 400 μLPEG300 → 50 μL Tween 80 → 450 μL Saline) Injection Formulation 3: DMSO : Corn oil = 10 : 90 (i.e. 100 μL DMSO → 900 μL Corn oil) Example: Take the Injection Formulation 3 (DMSO : Corn oil = 10 : 90) as an example, if 1 mL of 2.5 mg/mL working solution is to be prepared, you can take 100 μL 25 mg/mL DMSO stock solution and add to 900 μL corn oil, mix well to obtain a clear or suspension solution (2.5 mg/mL, ready for use in animals). View More
Injection Formulation 4: DMSO : 20% SBE-β-CD in saline = 10 : 90 [i.e. 100 μL DMSO → 900 μL (20% SBE-β-CD in saline)] Oral Formulations
Oral Formulation 1: Suspend in 0.5% CMC Na (carboxymethylcellulose sodium) Oral Formulation 2: Suspend in 0.5% Carboxymethyl cellulose Example: Take the Oral Formulation 1 (Suspend in 0.5% CMC Na) as an example, if 100 mL of 2.5 mg/mL working solution is to be prepared, you can first prepare 0.5% CMC Na solution by measuring 0.5 g CMC Na and dissolve it in 100 mL ddH2O to obtain a clear solution; then add 250 mg of the product to 100 mL 0.5% CMC Na solution, to make the suspension solution (2.5 mg/mL, ready for use in animals). View More
Oral Formulation 3: Dissolved in PEG400 (Please use freshly prepared in vivo formulations for optimal results.) |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.8047 mL | 14.0233 mL | 28.0466 mL | |
| 5 mM | 0.5609 mL | 2.8047 mL | 5.6093 mL | |
| 10 mM | 0.2805 mL | 1.4023 mL | 2.8047 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
Products are for research use only; We do not sell to patients
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