Size | Price | Stock | Qty |
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250mg |
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500mg |
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1g |
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2g |
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5g |
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Other Sizes |
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Purity: ≥98%
Meclofenoxate (also known as Centrophenoxine) HCl is a potent nootropic agent and an anti-aging drug used to treat the symptoms of senile dementia and Alzheimer's disease, and also inhibits the activity of cholinephosphotransferase. Meclofenoxate hydrochloride, an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA), has been shown to improve memory, have a mentally stimulating effect, and improve general cognition.
References |
Age Ageing.1977 May;6(2):123-31.
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Molecular Formula |
C12H17CL2NO3
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Molecular Weight |
294.17
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CAS # |
3685-84-5
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Related CAS # |
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Appearance |
Typically exists as solids (or liquids in special cases) at room temperature
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SMILES |
ClC1C([H])=C([H])C(=C([H])C=1[H])OC([H])([H])C(=O)OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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InChi Key |
FIVHOHCAXWQPGC-UHFFFAOYSA-N
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InChi Code |
InChI=1S/C12H16ClNO3.ClH/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11;/h3-6H,7-9H2,1-2H3;1H
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Chemical Name |
2-(Dimethylamino)ethyl 2-(4-chlorophenoxy)acetate hydrochloride
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Synonyms |
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HS Tariff Code |
2934.99.9001
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
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Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Solubility (In Vitro) |
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Solubility (In Vivo) |
Solubility in Formulation 1: 100 mg/mL (339.94 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
 (Please use freshly prepared in vivo formulations for optimal results.) |
Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 3.3994 mL | 16.9970 mL | 33.9939 mL | |
5 mM | 0.6799 mL | 3.3994 mL | 6.7988 mL | |
10 mM | 0.3399 mL | 1.6997 mL | 3.3994 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
NCT03961087 | UNKNOWN STATUS | Drug:Coenzyme Q10 Drug:MECLOFENOXATE |
Coenzyme Q10 Hepatic Encephalopathy Intellectual Functioning Disability |
Zagazig University | 2019-05-23 | Not Applicable |