| Size | Price | Stock | Qty |
|---|---|---|---|
| 50mg |
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| 100mg |
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| Other Sizes |
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| ln Vitro |
Cymbopogon schoenanthus (C. schoenanthus) produced piperitone, which was isolated[1].
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|---|---|
| ln Vivo |
Callosobruchus maculatus (C. maculatus) at various developmental stages are used to test the insecticidal activity of crude essential oil extracted from Cymbopogon schoenanthus and of its principal constituent, piperitone. Adult C. maculatus is toxic to piperitone; the LC50 value is 1.6 μL/L. While piperitone is less harmful to individuals growing inside the seeds than the crude extract, it still inhibits the development of freshly laid eggs and neonate larvae. The most potent ovicidal activity is seen in piperitone. At 6.7 μL/L, every egg was destroyed. All of the neonate larvae are killed by piperitone (10 μM)[1].
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| Animal Protocol |
Animal/Disease Models: Fifty pairs of C. maculatus adults[1]
Doses: 6.7, 10, 16.7 or 33.3 μL/L Route of Administration: 24 hrs (hours) Experimental Results: Piperiton was more toxic than crude oil because the LC50 recorded was 1.6 μL/L for Piperitone vs. 2.7 μL/L for the crude oil. |
| References |
| Molecular Formula |
C10H16O
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|---|---|
| Molecular Weight |
152.23
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| Exact Mass |
152.12
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| Elemental Analysis |
C, 78.90; H, 10.59; O, 10.51
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| CAS # |
89-81-6
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| Appearance |
Solid powder
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| SMILES |
CC1=CC(=O)C(CC1)C(C)C
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| InChi Key |
YSTPAHQEHQSRJD-UHFFFAOYSA-N
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| InChi Code |
InChI=1S/C10H16O/c1-7(2)9-5-4-8(3)6-10(9)11/h6-7,9H,4-5H2,1-3H3
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| Chemical Name |
3-methyl-6-propan-2-ylcyclohex-2-en-1-one
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| Synonyms |
3 Carvomenthenone; Piperitone; 3-Carvomenthenone; NSC251528; NSC 251528; NSC-251528
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
DMSO: 100 mg/mL (656.90 mM)
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: ≥ 2.5 mg/mL (16.42 mM) (saturation unknown) in 10% DMSO + 40% PEG300 + 5% Tween80 + 45% Saline (add these co-solvents sequentially from left to right, and one by one), clear solution.
For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 400 μL PEG300 and mix evenly; then add 50 μL Tween-80 to the above solution and mix evenly; then add 450 μL normal saline to adjust the volume to 1 mL. Preparation of saline: Dissolve 0.9 g of sodium chloride in 100 mL ddH₂ O to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (16.42 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. View More
Solubility in Formulation 3: ≥ 2.5 mg/mL (16.42 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. |
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 6.5690 mL | 32.8450 mL | 65.6901 mL | |
| 5 mM | 1.3138 mL | 6.5690 mL | 13.1380 mL | |
| 10 mM | 0.6569 mL | 3.2845 mL | 6.5690 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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