Size | Price | Stock | Qty |
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5g |
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Other Sizes |
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ln Vitro |
In capillary electrophoresis, tetradecyltrimethylammonium bromide (TTAB; TTABr) is being used more frequently as a surface active aid to help separate anionic species derived from acids. For optimal effects, tetradecyltrimethylammonium bromide has been found to need a minimum concentration of about 0.4 mM. This concentration has been selected because it is near the critical micelle concentration (CMC), which is thought to be necessary for the formation of "hemimicelles" on the capillary inner wall[3].
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References |
[1]. Dopierala K, et al. The effect of molecular structure on the surface properties of selected quaternary ammonium salts. J Colloid Interface Sci. 2008;321(1):220-226.
[2]. N. Gorski, et al. Mixtures of Nonionic and Ionic Surfactants. The Effect of Counterion Binding in Mixtures of Tetradecyldimethylamine Oxide and Tetradecyltrimethylammonium Bromide. Langmuir 1994, 10, 8, 2594-2603. [3]. Cocke DL, et al. The surface properties of tetradecyltrimethylammonium bromide observed by capillary electrophoresis. J Chromatogr Sci. 2002;40(4):187-190. |
Molecular Formula |
C17H38BRN
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Molecular Weight |
336.39
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CAS # |
1119-97-7
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Related CAS # |
Tetradecyltrimethylammonium-d29 bromide;95523-73-2;Tetradecyltrimethylammonium-d38 bromide;95523-72-1
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Appearance |
Typically exists as solids (or liquids in special cases) at room temperature
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SMILES |
[Br-].[N+](C([H])([H])[H])(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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HS Tariff Code |
2934.99.9001
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Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture and light. |
Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Solubility (In Vitro) |
H2O: 125 mg/mL (371.59 mM)
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Solubility (In Vivo) |
Solubility in Formulation 1: 50 mg/mL (148.64 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
 (Please use freshly prepared in vivo formulations for optimal results.) |
Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
1 mM | 2.9727 mL | 14.8637 mL | 29.7274 mL | |
5 mM | 0.5945 mL | 2.9727 mL | 5.9455 mL | |
10 mM | 0.2973 mL | 1.4864 mL | 2.9727 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration: mg/mL;
Method for preparing DMSO stock solution: mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation::Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.