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ACTH (1-14) (TFA) (Adrenocorticotropic Hormone Fragment 1-14 TFA)

Cat No.:V77293 Purity: ≥98%
ACTH (1-14) (TFA) is a bioactive peptide fragment of adrenocorticotropic hormone, which promotes the release of cortisol.
ACTH (1-14) (TFA) (Adrenocorticotropic Hormone Fragment 1-14 TFA)
ACTH (1-14) (TFA) (Adrenocorticotropic Hormone Fragment 1-14 TFA) Chemical Structure Product category: Adrenergic Receptor
This product is for research use only, not for human use. We do not sell to patients.
Size Price Stock Qty
1mg
5mg
10mg
Other Sizes

Other Forms of ACTH (1-14) (TFA) (Adrenocorticotropic Hormone Fragment 1-14 TFA):

  • ACTH 1-14
Official Supplier of:
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Top Publications Citing lnvivochem Products
Product Description
ACTH (1-14) (TFA) is a bioactive peptide fragment of adrenocorticotropic hormone, which promotes the release of cortisol.
Biological Activity I Assay Protocols (From Reference)
ln Vitro
Adrenocorticotropic hormone (ACTH) is a tropic hormone that is secreted by the anterior pituitary. It controls the production of androgen and cortisol and is linked to Cushing syndrome, Addison's illness, and Cushing disease[1].
References

[1]. Pharmacodynamic properties of a combination of met-enkephalin and alpha 1-13 adrenocorticotropic hormone. Med Arh. 2008;62(1):41-4.

These protocols are for reference only. InvivoChem does not independently validate these methods.
Physicochemical Properties
Molecular Formula
C79H110F3N21O22S
Molecular Weight
1794.90
Related CAS #
ACTH (1-14);25696-21-3
Appearance
Solid powder
HS Tariff Code
2934.99.9001
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.
Shipping Condition
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
Solubility Data
Solubility (In Vitro)
H2O :~100 mg/mL (~55.71 mM)
Solubility (In Vivo)
Solubility in Formulation 1: 25 mg/mL (13.93 mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.

 (Please use freshly prepared in vivo formulations for optimal results.)
Preparing Stock Solutions 1 mg 5 mg 10 mg
1 mM 0.5571 mL 2.7857 mL 5.5713 mL
5 mM 0.1114 mL 0.5571 mL 1.1143 mL
10 mM 0.0557 mL 0.2786 mL 0.5571 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.

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An example of molarity calculation using the molarity calculator is shown below:
What is the mass of compound required to make a 10 mM stock solution in 5 ml of DMSO given that the molecular weight of the compound is 350.26 g/mol?
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  • The answer of 17.513 mg appears in the Mass box. In a similar way, you may calculate the volume and concentration.

Dilution Calculator allows you to calculate how to dilute a stock solution of known concentrations. For example, you may Enter C1, C2 & V2 to calculate V1, as detailed below:

What volume of a given 10 mM stock solution is required to make 25 ml of a 25 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=25 μM, V2=25 ml and V1 is the unknown:
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Note: Chemical formula is case sensitive: C12H18N3O4  c12h18n3o4
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In vivo Formulation Calculator (Clear solution)
Step 1: Enter information below (Recommended: An additional animal to make allowance for loss during the experiment)
Step 2: Enter in vivo formulation (This is only a calculator, not the exact formulation for a specific product. Please contact us first if there is no in vivo formulation in the solubility section.)
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Calculation results

Working concentration mg/mL;

Method for preparing DMSO stock solution mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation:Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O,mix and clarify.

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
             (2) Be sure to add the solvent(s) in order.

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