| Size | Price | Stock | Qty |
|---|---|---|---|
| 5mg |
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| 10mg |
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| Other Sizes |
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| Targets |
Microbial Metabolite
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|---|---|
| ln Vitro |
The process of electrons moving from oxidizing to reducing agents is catalyzed by glucose oxidases, a subclass of oxidoreductases. The enzyme glucose oxidase releases hydrogen peroxide (H2O2) by using oxygen as an external electron acceptor. A wide range of commercial procedures employ glucose oxidase, such as enhancing food items' color and flavor, prolonging their shelf life, extracting glucose from dehydrated eggs, and removing oxygen from various juices and drinks [4].
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| References |
[1]. Konishi T, et al. Safety evaluation of glucose oxidase from Penicillium chrysogenum [published correction appears in Regul Toxicol Pharmacol. 2013 Aug;66(3):300]. Regul Toxicol Pharmacol. 2013;66(1):13-23.
[2]. Leskovac V, et al. Glucose oxidase from Aspergillus niger: the mechanism of action with molecular oxygen, quinones, and one-electron acceptors. Int J Biochem Cell Biol. 2005;37(4):731-750. [3]. Wang M, et al. Recent Advances in Glucose-Oxidase-Based Nanocomposites for Tumor Therapy. Small. 2019;15(51):e1903895. [4]. Khatami SH, et al. Glucose oxidase: Applications, sources, and recombinant production [published online ahead of print, 2021 Apr 11]. Biotechnol Appl Biochem. 2021;10.1002/bab.2165. |
| Additional Infomation |
Beta-D-glucose is d-Glucopyranose with beta configuration at the anomeric centre. It has a role as an epitope and a mouse metabolite. It is an enantiomer of a beta-L-glucose.
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement. Glucose oxidase has been investigated for the treatment of Upper Respiratory Tract Infections. b-D-Glucose is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). (2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol has been reported in Humulus lupulus, Maclura pomifera, and other organisms with data available. Beta-D-Glucopyranose is the beta isoform of D-glucopyranose, a synthetic simple monosaccharide as an energy source. D-glucopyranose is oxidized in various tissues either under aerobic or anaerobic conditions through glycolysis, and the oxidation reaction produces carbon dioxide, water and ATP. Zymosan is an insoluble beta-1,3-glucan polysaccharide derived from, and structural component of, yeast cell walls, with potential immunostimulating activity. Upon administration, zymosan targets, binds to and activates certain Toll-like receptors, primarily TLR type 2 (TLR-2), on leukocytes and dectin-1 on macrophages. Activation of TLR2 and dectin-1 stimulates the release of pro-inflammatory mediators, and enhances innate immune responses. Beta-D-Glucose is a metabolite found in or produced by Saccharomyces cerevisiae. See also: Zymosans (annotation moved to). |
| Exact Mass |
154.026
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|---|---|
| CAS # |
9001-37-0
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| Related CAS # |
26874-89-5;133947-06-5
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| PubChem CID |
64689
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| Appearance |
Typically exists as solid at room temperature
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| Density |
1.5±0.1 g/cm3
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| Boiling Point |
513.7±50.0 °C at 760 mmHg
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| Flash Point |
226.8±23.6 °C
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| Vapour Pressure |
0.0±3.0 mmHg at 25°C
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| Index of Refraction |
1.603
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| LogP |
-0.75
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| Hydrogen Bond Donor Count |
5
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| Hydrogen Bond Acceptor Count |
6
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| Rotatable Bond Count |
1
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| Heavy Atom Count |
12
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| Complexity |
151
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| Defined Atom Stereocenter Count |
5
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| SMILES |
C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
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| InChi Key |
WQZGKKKJIJFFOK-VFUOTHLCSA-N
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| InChi Code |
InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
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| Chemical Name |
(2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
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| HS Tariff Code |
2934.99.9001
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| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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| Solubility (In Vitro) |
H2O :~50 mg/mL
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|---|---|
| Solubility (In Vivo) |
Solubility in Formulation 1: 50 mg/mL (Infinity mM) in PBS (add these co-solvents sequentially from left to right, and one by one), clear solution; with sonication.
(Please use freshly prepared in vivo formulations for optimal results.) |
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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