| Size | Price | |
|---|---|---|
| 500mg | ||
| 1g | ||
| Other Sizes |
| ln Vivo |
Neutrophil elastase inhibitor 3 (compound 13, 1 mg/kg of body weight, intravenous administration) significantly reduced the increase in pulmonary myeloperoxidase (MPO) activity and edema after traumatic hemorrhagic shock in rats.
|
|---|---|
| References |
| Molecular Formula |
C14H7BRCLNO2
|
|---|---|
| Molecular Weight |
336.567881822586
|
| CAS # |
1234707-32-4
|
| Appearance |
Typically exists as solid at room temperature
|
| SMILES |
N1C2=CC=CC(Cl)=C2C(=O)OC=1C1=CC=CC=C1Br
|
| HS Tariff Code |
2934.99.9001
|
| Storage |
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
|
| Solubility (In Vitro) |
May dissolve in DMSO (in most cases), if not, try other solvents such as H2O, Ethanol, or DMF with a minute amount of products to avoid loss of samples
|
|---|---|
| Solubility (In Vivo) |
Solubility in formula 1: (Saturation unknown) in Neutrophil elastase inhibitor 3 (compound 13) is dissolved in 10% DMSO[1]. (These co-solvents are added one by one from left to right). (Please use freshly prepared in vivo formulations for optimal results.)
|
| Preparing Stock Solutions | 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.9712 mL | 14.8558 mL | 29.7115 mL | |
| 5 mM | 0.5942 mL | 2.9712 mL | 5.9423 mL | |
| 10 mM | 0.2971 mL | 1.4856 mL | 2.9712 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.
Calculation results
Working concentration： mg/mL；
Method for preparing DMSO stock solution： mg drug pre-dissolved in μL DMSO (stock solution concentration mg/mL). Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:：Take μL DMSO stock solution, next add μL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O，mix and clarify.
(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.
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