Progesterone receptor (PR) is a member of the steroid/thyroid hormone-retinoid receptor superfamily of ligand-activated nuclear transcription factors.
The development, differentiation, and maintenance of female reproductive tissue depends heavily on progesterone receptor.The ability of the progesterone receptor to bind to a wide range of ligands results in a wide range of transcriptional responses, including full agonism, full antagonism, and several mixed profiles in between. Progesterone receptors, such as progesterone, cause the PR ligand binding domain (LBD) to change its conformation, which in turn controls subsequent gene regulatory cascades.
Human PR-A and PR-B are two different types of progesterone receptors that mediate the biological response to progesterone in humans.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V15733 | Tanaproget (NSP989) | 304853-42-7 | Tanaproget(NSP-989) is a novel, potent and non-steroidal progesterone receptor agonist with the potentiall to be used as a female contraception. |
|
V19639 | Desogestrel | 54024-22-5 | Desogestrel (Org-2969, Desogen; Org2969, Desogestrelum, Org 2969, Cerazette) is a synthetic progestin derivative approved as an oral contraceptive medication used in birth control pills for women. |
|
V20258 | Drospirenone | 67392-87-4 | Drospirenone (MSp; SH-470; ZK-30595; LF-111; Slynd; Yasminelle; Yaz; Nextstellis) is a synthetic progestogen approved for used as an oral contraceptive alone or in combination with other medicaitons (Trade name: Alone: Slynd; With estradiol: Angeliq; With ethinylestradiol: Yasmin, Yasminelle, Yaz, others With estetrol: Nextstellis). |
|
V15494 | Norethindrone enanthate | 3836-23-5 | Norethindrone enanthate (LG-202; NSC-9564; SH-393;LG202; NSC9564; SH393; Norigest) is the 17-O-enanthate ester of Norethindrone (Norethisterone), which is a synthetic progestin, anantigonadotropic agent and an orally activehormonal contraceptive used for birth control. |
|
V5585 | Promegestone | 34184-77-5 | Promegestone (R-5020; RU-5020; trade name Surgestone) is a progestin medication and a synthetic progestogen acting as an agonist of the progesterone receptor. |
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V26605 | Norethindrone | 68-22-4 | Norethindrone (Norethisterone; sold under many trade names) is a synthetic progestin used as an orally active contraceptive for birth controls. |
|
V26611 | Norgestimate | 35189-28-7 | Norgestimate is a synthetic progestin analog, an orally bioactive progestin with selective progestogenic activity and minimal androgenic effects. |
|
V3879 | Segesterone acetate | 7759-35-5 | Segesterone acetate (formerly known as ST1435;ST-1435 or nestorone; trade name:Annovera) is an agonist of progesterone receptor used as a female-contraceptive drug. |
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