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Progesterone Receptor

Progesterone Receptor

Progesterone receptor (PR) is a member of the steroid/thyroid hormone-retinoid receptor superfamily of ligand-activated nuclear transcription factors.

The development, differentiation, and maintenance of female reproductive tissue depends heavily on progesterone receptor.The ability of the progesterone receptor to bind to a wide range of ligands results in a wide range of transcriptional responses, including full agonism, full antagonism, and several mixed profiles in between. Progesterone receptors, such as progesterone, cause the PR ligand binding domain (LBD) to change its conformation, which in turn controls subsequent gene regulatory cascades.

Human PR-A and PR-B are two different types of progesterone receptors that mediate the biological response to progesterone in humans.

Progesterone Receptor related products

Structure Cat No. Product Name CAS No. Product Description
17α-Ethynyl-19-nor-Δ-5(6)-androsten-17β-ol-3-one (delta-5(6)-Norethindrone) V83993 17α-Ethynyl-19-nor-Δ-5(6)-androsten-17β-ol-3-one (delta-5(6)-Norethindrone) 22933-71-7
17α-Hydroxyprogesterone-13C3 (17-Hydroxyprogesterone-13C3; 17-OHP-13C3) V67772 17α-Hydroxyprogesterone-13C3 (17-Hydroxyprogesterone-13C3; 17-OHP-13C3) 1356154-92-1 17α-Hydroxyprogesterone-13C3 is a 13C (carbon 13)-labeled 17α-Hydroxyprogesterone.
17α-Hydroxyprogesterone-d8 (17-Hydroxyprogesterone-d8; 17-OHP-d8) V67766 17α-Hydroxyprogesterone-d8 (17-Hydroxyprogesterone-d8; 17-OHP-d8) 850023-80-2 17α-Hydroxyprogesterone-d8 is the deuterium labelled form of 17α-Hydroxyprogesterone.
Altrenogest-d5 (Allyltrenbolone-d5; Allyltrenbolone-d5; RU2267-d5) V77901 Altrenogest-d5 (Allyltrenbolone-d5; Allyltrenbolone-d5; RU2267-d5) Altrenogest-d5 is the deuterium labelled form of Altrenogest.
ARD-61 V67604 ARD-61 2316837-08-6 ARD-61 is a highly efficient and specific PROTAC androgen receptor (AR) degrader.
Desogestrel V19639 Desogestrel 54024-22-5 Desogestrel (Org-2969, Desogen; Org2969, Desogestrelum, Org 2969, Cerazette) is a synthetic progestin derivative approved as an oral contraceptive medication used in birth control pills for women.
Drospirenone V20258 Drospirenone 67392-87-4 Drospirenone (MSp; SH-470; ZK-30595; LF-111; Slynd; Yasminelle; Yaz; Nextstellis) is a synthetic progestogen approved for used as an oral contraceptive alone or in combination with other medicaitons (Trade name: Alone: Slynd; With estradiol: Angeliq; With ethinylestradiol: Yasmin, Yasminelle, Yaz, others With estetrol: Nextstellis).
Drospirenone-d4 V67773 Drospirenone-d4 2376035-94-6 Drospirenone-d4 is the deuterium labelled form of Drospirenone.
Dydrogesterone-d6 (dydrogesterone d6) V79659 Dydrogesterone-d6 (dydrogesterone d6) Dydrogesterone-d6 is the deuterated form of Dydrogesterone.
Gestodene-d6 (SHB 331-d6; WL 70-d6) V65080 Gestodene-d6 (SHB 331-d6; WL 70-d6) 1542211-40-4 Gestodene-d6 is the deuterated form of Gestodene.
Medroxyprogesterone-d3 (17α-Hydroxy-6α-methylprogesterone-d3; U8840-d3) V67771 Medroxyprogesterone-d3 (17α-Hydroxy-6α-methylprogesterone-d3; U8840-d3) 162462-69-3 Medroxyprogesterone-d3 is the deuterium labelled form of Medroxyprogesterone.
Melengestrol acetate V67765 Melengestrol acetate 2919-66-6 Melengestrol acetate is a progesterone analogue that works as an orally bioactive corticosteroid that promotes endometrial proliferation, maintenance of pregnancy, and delayed menstrual activity.
Melengestrol acetate-d2 V78844 Melengestrol acetate-d2 Melengestrol acetate-d2 is the deuterium labelled form of Melengestrol acetate.
Melengestrol acetate-d3 V76777 Melengestrol acetate-d3 Melengestrol acetate-d3 is the deuterium labelled form of Melengestrol acetate.
Melengestrol acetate-d6 V79088 Melengestrol acetate-d6 Melengestrol acetate-d6 is the deuterium labelled form of Melengestrol acetate.
Norethindrone V26605 Norethindrone 68-22-4 Norethindrone (Norethisterone; sold under many trade names) is a synthetic progestin used as an orally active contraceptive for birth controls.
Norethindrone enanthate V15494 Norethindrone enanthate 3836-23-5 Norethindrone enanthate (LG-202; NSC-9564; SH-393;LG202; NSC9564; SH393; Norigest) is the 17-O-enanthate ester of Norethindrone (Norethisterone), which is a synthetic progestin, anantigonadotropic agent and an orally activehormonal contraceptive used for birth control.
Norgestimate V26611 Norgestimate 35189-28-7 Norgestimate is a synthetic progestin analog, an orally bioactive progestin with selective progestogenic activity and minimal androgenic effects.
Norgestimate-d6 (Norgestimate-d6) V64134 Norgestimate-d6 (Norgestimate-d6) 1263194-12-2 Norgestimate-d6 is the deuterium labelled form of Norgestimate.
Norgestrel-d6 (levonorgestrel d6) V63506 Norgestrel-d6 (levonorgestrel d6) 2376035-98-0 Norgestrel-d6 is the deuterated form of Levonorgestrel.
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