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NF-κB

NF-κB

Nuclear factor-κB (NF-κB)/Rel proteins include NF-κB2 p52/p100, NF-κB1 p50/p105, c-Rel, RelA/p65, and RelB.These proteins perform as two-component transcription factors that control gene expression and have an impact on a variety of biological processes, such as innate and acquired immunity, inflammation, stress responses, B-cell development, and lymphoid organogenesis.The immune system's reaction to infection is significantly regulated by NF-B. In addition, the etiology of chronic inflammatory illnesses such inflammatory bowel disease, rheumatoid arthritis, and asthma is influenced by the activation of the NF-B pathway. Septic shock, autoimmune and inflammatory disorders, viral infections, and poor immunological development have all been connected to faulty NF-B regulation.

NF-κB related products

Structure Cat No. Product Name CAS No. Product Description
Dehydroevodiamine V29658 Dehydroevodiamine 67909-49-3 Dehydroevodiamine is a naturally occurring quinazoline alkaloid isolated from the unripe fruit of Evodia rutaecarpa (Rutaceae) with a variety of biological effects such as hypotensive, negative chronotropic, ion channel depressa.
Demethyleneberberine chloride V56104 Demethyleneberberine chloride 16705-03-6 Demethyleneberberine chloride is a natural mitochondria-targeted antioxidant.
Deoxyelephantopin V60127 Isodeoxyelephantopin 29307-03-7 Deoxyelephantopin, a naturally occurring bioactive sesquiterpene lactone from Elephantopus scaber, has demonstrated encouraging anticancer effects against a variety of cancers.
Deoxythymidine-5'-triphosphate-13C10,15N2 dilithium (dTTP-13C10,15N2 dilithium) V82260 Deoxythymidine-5'-triphosphate-13C10,15N2 dilithium (dTTP-13C10,15N2 dilithium) 2483830-18-6 Deoxythymidine-5'-triphosphate-13C10,15N2 (dTTP-13C10,15N2) dilithium is 13C and 15N labeled Deoxythymidine-5'-triphosphate .
Dihydrodaidzin V82261 Dihydrodaidzin 121927-96-6 Dihydrodaidzin is an isoflavanone that can be extracted from soybeans.
Drpitor1a V85135 Drpitor1a 73326-98-4
Eleutheroside E V30628 Eleutheroside E 39432-56-9 Eleutheroside E is an important component of Acanthopanax, which has anti~inflammatory and protective effects on ischemic heart.
Enzymatically modified isoquercitrin V7122 Enzymatically modified isoquercitrin 482-35-9 Enzymatically modified isoquercitrin, formerly known as EMIQ, is a flavonoid.
Ethacrynic acid V8949 Ethacrynic acid 58-54-8 Ethacrynic acid (MK-595; NSC-624008; NSC-85791;Hydromedin; Crinuryl; Mingit;Etacrinic acid; Otacril Reomax; Taladren; Edecrin) isa high ceiling loop diuretic acting as a Na+/K+/2Cl- cotransporter NKCC2 inhibitor.
Ethacrynic acid sodium (Etacrynic acid sodium; Sodium etacrynate) V71488 Ethacrynic acid sodium (Etacrynic acid sodium; Sodium etacrynate) 6500-81-8 Ethacrynic acid (Etacrynic acid sodium) sodium is a diuretic.
Eupenicisirenin C V85245 Eupenicisirenin C 2968309-12-6
Evodiamine V2020 Evodiamine 518-17-2 Evodiamine (d-Evodiamine;Q-100579;SC-16015; Evo; Isoevodiamine) is a naturally occuring quinazolinocarboline alkaloid extracted from the fruit of Evodiae Fructus, exhibiting moderate antiproliferative activities against various human tumor cells.
FA-Ala-Arg V82271 FA-Ala-Arg 76079-06-6 FA-Ala-Arg is a dipeptide with a furanoyl group.
FITC-labeled Keap1-Nrf2 probe V79428 FITC-labeled Keap1-Nrf2 probe FITC-labelled Keap1-Nrf2 probe is a FITC-labeled Keap1-Nrf2 probe.
Fumiquinazoline D V82264 Fumiquinazoline D 140715-86-2 Fumiquinazoline D is a secondary metabolite (SM, chemical compound) and a mycotoxin.
Gemcitabine triphosphate (dFdCTP) V82300 Gemcitabine triphosphate (dFdCTP) 110988-86-8 Gemcitabine triphosphate (dFdCTP) is one of the two intracellular nucleoside metabolites of Gemcitabine.
GSK2332255B V82280 GSK2332255B 1366233-41-1 GSK2332255B is a potent and specific TRPC3 and TRPC6 antagonist (inhibitor) with IC50 of 5 nM and 4 nM for rat TRPC3 and rat TRPC6.
Hederagenin V14077 Hederagenin 465-99-6 Hederagenin is a triterpenoid saponin that can inhibit the expression of iNOS, COX-2, and NF-κB in cells caused by LPS stimulation.
Hexacosanoic acid-d4 V82286 Hexacosanoic acid-d4 1208837-79-9 Hexacosanoic acid-d4 is the deuterated form of Hexacosanoic acid.
Hexacosanoic acid-d4-1 V82289 Hexacosanoic acid-d4-1 1194984-85-4 Hexacosanoic acid-d4-11 is the deuterated form of Hexacosanoic acid.
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