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Microtubule(Tubulin)

Microtubule(Tubulin)

Microtubules are a component of the cytoskeleton, found throughout the cytoplasm.These highly dynamic tubular tubulin polymers have an average length of 25 m and a maximum growth length of 50 micrometers. A microtubule has an inner diameter of 12 nm and an outer diameter of about 24 nm. Alpha and beta tubulin combine to form a dimer, which is then polymerized to form microtubules, which are found in eukaryotic cells. One of many members of a small family of globular proteins is tubulin.The alpha-, beta-, gamma-, delta-, and epsilon-tubulins are among the five distinct families that make up the tubulin superfamily, and a sixth family is only found in kinetoplastid protozoa. The proteins that make up microtubules, -tubulin and -tubulin, are the most prevalent members of the tubulin family. Microtubules play a crucial role in many cellular processes. They assist in keeping the cell's structure intact.

Microtubule(Tubulin) related products

Structure Cat No. Product Name CAS No. Product Description
Tilavonemab (ABBV-8E12; C2N-8E12) V55249 Tilavonemab (ABBV-8E12; C2N-8E12) 2096513-89-0 Tilavonemab (ABBV-8E12) is a humanized anti-tau antibody that binds to amino acid (AA)s 25-30 near the N-terminus of the tau protein.
TN-16 V16531 TN-16 33016-12-5 TN-16 (TN16; NSC-239274) is a potent tubulin inhibitor (antitubulin/antimitotic agent) with anticancer activity.
Tubulin inhibitor 15 V75822 Tubulin inhibitor 15 2767446-36-4 Tubulin inhibitor 15 is a potent tubulin inhibitor.
Tubulin inhibitor 16 V75820 Tubulin inhibitor 16 2767446-32-0 Tubulin inhibitor 16 is a potent tubulin inhibitor.
Tubulin inhibitor 31 V79473 Tubulin inhibitor 31 Tubulin inhibitor 31 is a potent tubulin inhibitor (antagonist) with IC50 of 4 µM.
Tubulin inhibitor 34 V79656 Tubulin inhibitor 34 Tubulin inhibitor 34 (compound b5) is an effective anticancer agent.
Tubulin inhibitor 36 V80143 Tubulin inhibitor 36 Tubulin inhibitor 36 (Compound 10) is a new type of potent tubulin inhibitor that can inhibit tubulin polymerization and induce cell apoptosis.
Tubulin inhibitor 37 V81644 Tubulin inhibitor 37 Tubulin inhibitor 37 (compound 12) is a Tubulin inhibitor that can effectively inhibit Tubulin polymerization (IC50=1.3 µM).
Tubulin inhibitor 38 V81645 Tubulin inhibitor 38 Tubulin inhibitor 38 (compound 14) is a tetrazolium-based tubulin (Microtubule/Tubulin) inhibitor (antagonist) with antiproliferation ability.
Tubulin inhibitor 40 V84607 Tubulin inhibitor 40
Tubulin inhibitor 41 V83612 Tubulin inhibitor 41 2770273-12-4
Tubulin inhibitor 6 V39080 Tubulin inhibitor 6 105925-39-1 Tubulin inhibitor 6 (Compound 14b) is a novel and potent tubulin inhibitor (mitotic inhibitor or tubulin destabilizer) with anticancer activity.
Tubulin polymerization-IN-11 V51291 Tubulin polymerization-IN-11 2470063-59-1 Tubulin polymerization-IN-11 is a novel and selective inhibitor of tubulin polymerization with an IC50 value of 3.4 µM.
Tubulin polymerization-IN-12 V34711 Tubulin polymerization-IN-12 2377301-45-4 Tubulin polymerization-IN-12 is an inhibitor (blocker/antagonist) of tubulin polymerization (IC50=0.75 μM).
Tubulin polymerization-IN-2 V75812 Tubulin polymerization-IN-2 2873399-22-3 Tubulin polymerization-IN-2 is a potent anti-cancer active molecule targeting β-tubulin with IC50 of 0.92 μM.
Tubulin polymerization-IN-33 V78673 Tubulin polymerization-IN-33 Tubulin polymerization-IN-33 is an inhibitor (blocker/antagonist) of [1,2] oxazoloisoindole tubulin polymerization and has high anti-proliferation activity against NCI series cancer/tumor cells.
Tubulin polymerization-IN-34 V81646 Tubulin polymerization-IN-34 Tubulin polymerization-IN-34 is a [1,2] oxazole-isoindole tubulin polymerization inhibitor that displays high selectivity for the marginal zone lymphoma VL51 cell line.
Tubulin polymerization-IN-35 V81647 Tubulin polymerization-IN-35 Tubulin polymerization-IN-35 is a [1,2] oxazole-isoindole tubulin polymerization inhibitor that displays high selectivity for the marginal zone lymphoma VL51 cell line.
Tubulin polymerization-IN-38 V34710 Tubulin polymerization-IN-38 1005192-31-3 Tubulin polymerization-IN-38 is an analogue of Tubulysin.
Tubulin polymerization-IN-39 V79779 Tubulin polymerization-IN-39 Tubulin polymerization-IN-39 is a tubulin polymerization inhibitor (IC50= 4.9 μM).
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