Microtubules are a component of the cytoskeleton, found throughout the cytoplasm.These highly dynamic tubular tubulin polymers have an average length of 25 m and a maximum growth length of 50 micrometers. A microtubule has an inner diameter of 12 nm and an outer diameter of about 24 nm. Alpha and beta tubulin combine to form a dimer, which is then polymerized to form microtubules, which are found in eukaryotic cells. One of many members of a small family of globular proteins is tubulin.The alpha-, beta-, gamma-, delta-, and epsilon-tubulins are among the five distinct families that make up the tubulin superfamily, and a sixth family is only found in kinetoplastid protozoa. The proteins that make up microtubules, -tubulin and -tubulin, are the most prevalent members of the tubulin family. Microtubules play a crucial role in many cellular processes. They assist in keeping the cell's structure intact.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V55254 | Tubulin polymerization-IN-42 | 2640220-51-3 | Tubulin polymerization-IN-42 (compound 10j) is an indole-substituted furanone and a tubulin polymerization inhibitor (antagonist) with anti-cancer effect. | |
V55260 | Tubulin polymerization-IN-43 | 2773345-90-5 | Tubulin polymerization-IN-43 (compound 15h) is a tubulin polymerization inhibitor. | |
V79964 | Tubulin polymerization-IN-44 | Tubulin polymerization-IN-44 (7w) is a potent and potent tubulin inhibitor (antagonist) with IC50 of 0.21 μM. | ||
V79951 | Tubulin polymerization-IN-45 | Tubulin polymerization-IN-45 is a tubulin targeting agent and a tubulin polymerization inhibitor. | ||
V79465 | Tubulin polymerization-IN-46 | Tubulin polymerization-IN-46 (compound 9q) is a microtubule/Tubulin inhibitor that can suppress tubulin polymerization and causes apoptosis. | ||
V55253 | Tubulin polymerization-IN-47 | 2834087-62-4 | Tubulinpolymerization-IN-47 (Compound 4h) is a tubulin polymerization inhibitor and mitosis inhibitor. | |
V79892 | Tubulin polymerization-IN-48 | Tubulin polymerization-IN-48 (Compound 4k) is a tubulin polymerization inhibitor. | ||
V79883 | Tubulin polymerization-IN-49 | Tubulin polymerization-IN-49 (compound 12d) is a potent inhibitor of tubulin polymerization. | ||
V79105 | Tubulin polymerization-IN-50 | Tubulin polymerization-IN-50 (compound 7n) is a tubulin polymerization inhibitor (antagonist) with IC50 of 5.05 μM in SK-Mel-28 cells. | ||
V55248 | Tubulin polymerization-IN-52 | 2108615-05-8 | Tubulin polymerization-IN-52 (compound SC23) is a potent inhibitor of tubulin polymerization with IC50 of 2.9 μM. | |
V81648 | Tubulin polymerization-IN-53 | Tubulin polymerization-IN-53 is an inhibitor (blocker/antagonist) of β-tubulin polymerization. | ||
V75813 | Tubulin polymerization-IN-55 | 2942396-29-2 | Tubulin polymerization-IN-55 is an effective inhibitor of Tubulin Polymerization. | |
V75827 | Tubulin polymerization-IN-57 | 95385-38-9 | Tubulin polymerization-IN-57 (compound 5a) is a tubulin inhibitor and is an α-naphthoxy-substituted carbendazim analogue. | |
V84220 | Tubulin polymerization-IN-58 | |||
V84232 | Tubulin polymerization-IN-59 | |||
V75826 | Tubulin polymerization-IN-8 | 2768485-08-9 | Tubulin aggregation-IN-8 (compound IIc) is a potent inhibitor of tubulin aggregation. | |
V83380 | Tubulin polymerization/V-ATPase-IN-1 | |||
V81649 | Tubulin/AKT1-IN-1 | Tubulin/AKT1-IN-1 (Compound D1-1) is an inhibitor (blocker/antagonist) of tubulin polymerization and AKT pathway activation. | ||
V79698 | Tubulin/HDAC-IN-2 | Tubulin/HDAC-IN-2 (Compound II-19k) is a dual (bifunctional) inhibitor of Tubulin and HDAC, with IC50s of 0.403 μM, 0.591 μM, 3.552 μM, and 0.459 μM for HDAC1/2/3/6 respectively. | ||
V78534 | Tubulin/HDAC-IN-3 | Tubulin/HDAC-IN-3 (compound 12a) is a potent dual tubulin/HDAC inhibitor. |