PPAR

Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD
GPCR & G Protein

5-HT Receptor Adenosine Receptor Adenylate Cyclase Adrenergic Receptor Angiotensin Receptor APJ Bombesin Receptor Bradykinin Receptor cAMP Cannabinoid Receptor CaSR CCK receptor CCR CGRP Receptor CRFR CXCR Dopamine Receptor EBI2 Endothelin Receptor Formyl Peptide Receptor Free Fatty Acid Receptor G protein-coupled Bile Acid Receptor GCGR GHSR GLP Receptor Glucagon Receptor GnRH Receptor GPCR19 GPR GPR109A Guanylate Cyclase Hedgehog(Smoothened) ROCK Histamine Receptor ICMT Leukotriene Receptor LPA Receptor LPL Receptor LTR mAChR Melanocortin Receptor Melatonin Receptor mGluR Motilin Receptor MRGPR MT Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor NPY receptor Opioid Receptor OX Receptor Oxytocin Receptor P2Y Receptor PAFR PAR PKD PKG Prostaglandin Receptor Ras RGS Protein S1P Receptor SGLT Sigma Receptor Somatostatin Receptor TAAR TSH Receptor Urotensin Receptor Vasopressin Receptor

+MORE

PPAR

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptor superfamily ligand-activated transcription factors that include the following three subtypes: PPAR, PPAR, and PPAR/. Higher organisms' cellular differentiation, development, metabolism (carbohydrate, lipid, and protein), as well as tumorigenesis, are all crucially regulated by PPARs. All PPARs bind to particular regions of the target genes' DNA through heterodimerization with the retinoid X receptor (RXR). Triglyceride levels are reduced and energy homeostasis is regulated when PPAR- is activated. PPAR- activation improves the metabolism of glucose, whereas PPAR-/ activation improves the metabolism of fatty acids.

PPAR related products

Cat No.	Product Name	CAS No.	Product Description
V85378	BAY-5094	2891706-78-6
V85379	BAY-5516	2891706-79-7
V85720	BAY-9683	2891706-83-3
V51330	Bezafibrate-d6	1219802-74-0	Bezafibrate-d6 is the deuterium labeled Bezafibrate.
V3800	BMS-711939	1000998-62-8	BMS-711939, an analog of BMS-687453, is a novel potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with an EC50 and IC50 of 4 nM for human PPARα and >1000-fold selectivity vs human PPARγ (EC50 of 4.5 μM) and PPARδ (EC50 > 100 μM) in PPAR-GAL4 transactivation assays.
V51348	Bocidelpar (ASP-0367; MA-0211)	2095128-20-2	Bocidelpar is a peroxisome proliferator-activated receptor delta (PPAR-δ) modulator.
V51347	Caulophyllogenin	52936-64-8	Caulophyllogenin is a novel and potent triterpene saponin extracted from M. polimorpha.
V51340	CAY-10410	596104-94-8	CAY10410 (11-Oxo-prosta-5Z), a 15d-PGJ2 analog, is a novel agonist of PPARγ.
V83405	CAY10506	292615-75-9
V83362	CAY10514	868526-38-9
V4093	Choline Fenofibrate	856676-23-8	Choline fenofibrate (formerly also known as ABT-335 or choline salt of fenofibric acid) is a novel, synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity that acts as anPPARαagonist.
V54369	Ciprofibrate impurity A	1474058-89-3	Ciprofibrate impurity A is an impurity in Ciprofibrate.
V18511	Clofibrate	637-07-0	Clofibrate (Atromid-S)is a novel and potent lipid-lowering agent acting as anagonist of PPAR with EC50s of 50 μM, ∼500 μM for murine PPARα and PPARγ, and 55 μM, ∼500 μM for human PPARα and PPARγ, respectively.
V51331	Clofibrate-d4	1189654-03-2	Clofibrate-d4, deuterium labeled Clofibrate.
V51349	Clofibric acid-d4 (Chlorofibrinic acid-d4)	184991-14-7	Clofibric acid-d4 (Chlorofibrinic acid-d4), deuterium labeled Clofibric acid.
V52604	Clofibric acid-d4 (Chlorofibric acid-d4)	1184991-14-7	Clofibric acid-d4 is the deuterated form of Clofibric acid.
V54370	CRX000227	686769-92-6	CRX000227 is a PPAR modulator.
V2124	Daidzein	486-66-8	Daidzein is a naturally occuring isoflavone phytoestrogen isolated from Leguminosae, used as a component of foods and dietary supplements.
V51341	Daidzein-d4	1219803-57-2	Daidzein-d4 is the deuterium labelled form of Daidzein.
V51339	DS-6930	1242328-82-0	DS-6930 is a novel agonist of PPARγ, with an EC50 of 41 nM. DS-6930 has the potential to significantly lower plasma glucose (PG) while having fewer negative effects related to PPARγ than Rosiglitazone.