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Nucleoside Antimetabolite(Analog)

Nucleoside Antimetabolite(Analog)

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite(Analog) related products

Structure Cat No. Product Name CAS No. Product Description
2'-Deoxy-2'-fluoro-N3-(4-hydroxybenzyl)uridine V80126 2'-Deoxy-2'-fluoro-N3-(4-hydroxybenzyl)uridine 2'-Deoxy-2'-fluoro-N3-(4-hydroxybenzyl)uridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)uridine V77546 2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)uridine 2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)uridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine V79514 2'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine 2'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]uridine V80382 2'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]uridine 2'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]uridine is a uridine analog.
2'-Deoxy-2'-fluoro-N3-[(pyrid-4-yl)methyl]uridine V80383 2'-Deoxy-2'-fluoro-N3-[(pyrid-4-yl)methyl]uridine 2'-Deoxy-2'-fluoro-N3-[(pyrid-4-yl)methyl]uridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoro-N3-[3-(tert-butoxycarbonyl) amino]propyluridine V80046 2'-Deoxy-2'-fluoro-N3-[3-(tert-butoxycarbonyl) amino]propyluridine 2'-Deoxy-2'-fluoro-N3-[3-(tert-butoxycarbonyl) amino]propyluridine is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoroadenosine 5'-monophosphate triethylammonium V79305 2'-Deoxy-2'-fluoroadenosine 5'-monophosphate triethylammonium 2'-Deoxy-2'-fluoroadenosine 5'-monophosphate (triethylammonium) is an analogue of purine nucleoside.
2'-Deoxy-2'-fluoroguanosine 5'-monophosphate triethyl ammonium V79304 2'-Deoxy-2'-fluoroguanosine 5'-monophosphate triethyl ammonium 2'-Deoxy-2'-fluoroguanosine 5'-monophosphate triethyl ammonium is an analogue of purine nucleoside.
2'-Deoxy-2'-fluorouridine 5'-monophosphate triethyl ammonium V77548 2'-Deoxy-2'-fluorouridine 5'-monophosphate triethyl ammonium 2'-Deoxy-2'-fluorouridine 5'-monophosphate triethyl ammonium is an analogue of purine nucleoside.
2'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine V77549 2'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine 2'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate (triethylamine) is an analogue of purine nucleoside.
2'-O,4'-C-Methyleneadenosine 5'-monophosphate triethylammonium V77551 2'-O,4'-C-Methyleneadenosine 5'-monophosphate triethylammonium 2'-O,4'-C-Methyleneadenosine 5'-monophosphate (triethylammonium) is an analogue of purine nucleoside.
2'-O-(2-Methoxyethyl)guanosine 5'-triphosphate ammonium V77550 2'-O-(2-Methoxyethyl)guanosine 5'-triphosphate ammonium 2'-O-(2-Methoxyethyl)guanosine 5'-triphosphate (ammonium) is an analogue of purine nucleoside.
2'-O-(3-Azidopropyl)-5-azacytidine V80416 2'-O-(3-Azidopropyl)-5-azacytidine 2'-O-(3-Azidopropyl)-5-azacytidine is an analogue of purine nucleoside.
2'-O-Acetyl-5'-O-benzoyl-3'-O-(2-methoxyethyl) uridine V79614 2'-O-Acetyl-5'-O-benzoyl-3'-O-(2-methoxyethyl) uridine 2'-O-Acetyl-5'-O-benzoyl-3'-O-(2-methoxyethyl) uridine is a uridine analog.
2'-O-Me-5-IU-3'-phosphoramidite V77553 2'-O-Me-5-IU-3'-phosphoramidite 2'-O-Me-5-IU-3'-phosphoramidite is an analogue of purine nucleoside.
2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium V77554 2'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium 2'-O-Methyl-5-methyluridine 5'-triphosphate (triethylammonium) is a thymidine analog.
2'-O-Methyladenosine 5'-monophosphate triethyl ammonium V77555 2'-O-Methyladenosine 5'-monophosphate triethyl ammonium 2'-O-Methyladenosine 5'-monophosphate triethyl ammonium is an adenine nucleoside analogue.
2,6-Bis(4-morpholinyl)-9-bD-ribofuranosyl-9H-purine V80111 2,6-Bis(4-morpholinyl)-9-bD-ribofuranosyl-9H-purine 2,6-Bis(4-morpholinyl)-9-bD-ribofuranosyl-9H-purine is an adenine nucleoside analogue.
2-(3-Methyln-propylidene hydrazino)adenosine V80158 2-(3-Methyln-propylidene hydrazino)adenosine 2-(3-Methyln-propylidene hydrazino) adenosine is an analogue of purine nucleoside.
2-(P-Cyanophenyl methylidene hydrazino) adenosine V80007 2-(P-Cyanophenyl methylidene hydrazino) adenosine 2-(P-Cyanophenyl methylidene hydrazino) adenosine is an analogue of purine nucleoside.
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