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Nucleoside Antimetabolite(Analog)

Nucleoside Antimetabolite(Analog)

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite(Analog) related products

Structure Cat No. Product Name CAS No. Product Description
3'-β-C-Methyl-2-thiouridine V80426 3'-β-C-Methyl-2-thiouridine 3'-β-C-Methyl-2-thiouridine is an analogue of purine nucleoside.
3,5'-Bis(Ot-butyldimethylsilyl)-2'-O-methyl-5-methyl cytidine V77595 3,5'-Bis(Ot-butyldimethylsilyl)-2'-O-methyl-5-methyl cytidine 3,5'-Bis(Ot-butyldimethylsilyl)-2'-O-methyl-5-methyl cytidine is a cytosine nucleoside analogue.
3,5-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl] cytidine V77596 3,5-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl] cytidine 3,5-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl] cytidine is an analogue of purine nucleoside.
3-Cyanovinyl-9-(5'-O-DMT-2'-deoxyribofuranosyl)carbazole V77607 3-Cyanovinyl-9-(5'-O-DMT-2'-deoxyribofuranosyl)carbazole 3-Cyanovinyl-9-(5'-O-DMT-2'-deoxyribofuranosyl)carbazole is an analogue of purine nucleoside.
3-Deaza-xylouridine V80436 3-Deaza-xylouridine 3-Deaza-xylouridine is an analogue of purine nucleoside.
4'-alpha-C-Azido-2',3'-bis(Ot-butyldimethylsilyl)uridine V77620 4'-alpha-C-Azido-2',3'-bis(Ot-butyldimethylsilyl)uridine 4'-alpha-C-Azido-2',3'-bis(Ot-butyldimethylsilyl)uridine is a uridine analog.
4-Amino-1-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide V80620 4-Amino-1-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide 4-Amino-1-(β-D-ribofurano syl)-7H-pyrrolo [2.3-d] pyrimidine-5-carboxamide is an analogue of purine nucleoside.
4-Amino-5-cyano-1-(2-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine V80621 4-Amino-5-cyano-1-(2-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine 4-Amino-5-cyano-1-(2-deoxy-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog.
4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine V78614 4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine 4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog things.
4-Deoxy-3'-deoxy-3'-fluoro uridine V77438 4-Deoxy-3'-deoxy-3'-fluoro uridine 4-Deoxy-3'-deoxy-3'-fluoro uridine is an analogue of purine nucleoside.
5'(R)-C-Methyl-5-fluorouridine V81070 5'(R)-C-Methyl-5-fluorouridine 5'(R)-C-Methyl-5-fluorouridine is a uridine analog.
5'(R)-C-Methyl-N6-methyladenosine V80608 5'(R)-C-Methyl-N6-methyladenosine 5'(R)-C-Methyl-N6-methyladenosine is an adenine nucleoside analog.
5'-DMTr-3'dA(Bz)-methylphosphonamidite V77633 5'-DMTr-3'dA(Bz)-methylphosphonamidite 5'-DMTr-3'dA(Bz)-methylphosphonami dite is an analogue of purine nucleoside.
5'-Homoadenosine V80708 5'-Homoadenosine 5'-Homoadenosine is an analogue of purine nucleoside.
5'-Homocytidine V80982 5'-Homocytidine 5'-Homocytidine is an analogue of purine nucleoside.
5'-O-(4,4'-Dimethoxy trityl)-2'-O-(2-methoxyethyl) inosine V77634 5'-O-(4,4'-Dimethoxy trityl)-2'-O-(2-methoxyethyl) inosine 5'-O-(4,4'-Dimethoxy trityl)-2'-O-(2-methoxyethyl) inosine is an analogue of purine nucleoside.
5'-O-(4,4'-Dimethoxytrityl)-3'-O-(2-methoxyethyl) uridine V77952 5'-O-(4,4'-Dimethoxytrityl)-3'-O-(2-methoxyethyl) uridine 5'-O-(4,4'-Dimethoxytrityl)-3'-O-(2-methoxyethyl) uridine is an analogue of purine nucleoside.
5'-O-Benzoyl-2',3'-di-O-acetyl-4'-C-fluoromethyluridine V77635 5'-O-Benzoyl-2',3'-di-O-acetyl-4'-C-fluoromethyluridine 5'-O-Benzoyl-2',3'-di-O-acetyl-4'-C-fluoromethyluridine is an analogue of purine nucleoside.
5'-O-Benzoyl-3'-O-(4-methoxybenzyl)-2'-O,4'-C-methyleneuridine V78894 5'-O-Benzoyl-3'-O-(4-methoxybenzyl)-2'-O,4'-C-methyleneuridine 5'-O-Benzoyl-3'-O-(4-methoxybenzyl)-2'-O,4'-C-methyleneuridine is an analogue of purine nucleoside.
5'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite V77636 5'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite 5'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite is an analogue of purine nucleoside.
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