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Nucleoside Antimetabolite(Analog)

Nucleoside Antimetabolite(Analog)

Nucleoside analogues are molecules that act like nucleosides in DNA synthesis.A variety of antiviral products are among them; they are used to stop viral replication in infected cells. Nucleoside analogues can be used to treat HIV, herpes simplex, hepatitis B, and hepatitis C. Once phosphorylated, they function as antimetabolites by resembling nucleotides closely enough to be incorporated into developing DNA strands.Chemotherapy agents, such as gemcitabine and 5-FU, are used to treat cancer using less selective nucleoside analogues. A metabolite, a different chemical that is produced as part of normal metabolism, can't be used when an antimetabolite is present. These substances frequently share structural similarities with the metabolite that they disrupt, such as the antifolates that prevent the absorption of folic acid. Antimetabolites are used as chemotherapy for cancer because their presence can have toxic effects on cells, such as halting cell growth and cell division.

Nucleoside Antimetabolite(Analog) related products

Structure Cat No. Product Name CAS No. Product Description
6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine V80234 6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine 6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is an analogue of purine nucleoside.
6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine V81011 6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine 6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is an analogue of purine nucleoside.
6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine V80949 6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine 6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog.
6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine V80979 6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine 6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is an analogue of purine nucleoside.
6-Amino-4-methoxy-1-(2-deoxy-aD-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine V80710 6-Amino-4-methoxy-1-(2-deoxy-aD-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine 6-Amino-4-methoxy-1-(2-deoxy-aD-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog.
6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine V80306 6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine 6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is an analogue of purine nucleoside.
6-Chloro-2-fluoropurine-9-bD-(3,5-bis-O-(p-toluoyl)-2-deoxy)riboside V77673 6-Chloro-2-fluoropurine-9-bD-(3,5-bis-O-(p-toluoyl)-2-deoxy)riboside 6-Chloro-2-fluoropurine-9-bD-(3,5-bis-O-(p-toluoyl)-2-deoxy)riboside is an analogue of purine nucleoside.
6-Chloro-N1-(trimethylsilylethoxymethyl)pseudouridine V77674 6-Chloro-N1-(trimethylsilylethoxymethyl)pseudouridine 6-Chloro-N1-(trimethylsilylethoxymethyl)pseudouridine is a uridine analog.
6-Deoxo-8-oxo-3'-deoxy-guanosine V81054 6-Deoxo-8-oxo-3'-deoxy-guanosine 2′-Deoxy-N-(2-furanylmethyl)guanosine is a guanine nucleoside analog.
6-Methoxypurine-9-beta-D-(3-methoxy riboside) V80611 6-Methoxypurine-9-beta-D-(3-methoxy riboside) 6-Methoxypurine-9-beta-D-(3-methoxy riboside) is an analogue of purine nucleoside.
6-Methoxypurine-9-β-D-5'(R)-C-methylriboside V80612 6-Methoxypurine-9-β-D-5'(R)-C-methylriboside 6-Methoxypurine-9-β-D-5'(R)-C-methylriboside is a hypoxanthine analogue.
6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine V80238 6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine 6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine is an analogue of purine nucleoside.
6-O-Methyl-2'-O-methylinosine V80613 6-O-Methyl-2'-O-methylinosine 6-O-Methyl-2'-O-methylinosine is an analogue of purine nucleoside.
6-S-(2-Cyanoethyl)-2'-deoxy-5'-O-DMTr--6-thioguanosine 3'-CED phosphoramidite V77793 6-S-(2-Cyanoethyl)-2'-deoxy-5'-O-DMTr--6-thioguanosine 3'-CED phosphoramidite 6-S-(2-Cyanoethyl)-2'-deoxy-5'-O-DMTr--6-thioguanosine 3'-CED phosphoramidite is an analogue of purine nucleoside.
7-(N-Acetylaminomethyl)-7-deazaguanosine V80478 7-(N-Acetylaminomethyl)-7-deazaguanosine 7-(N-Acetylaminomethyl)-7-deazaguanosine is an analogue of purine nucleoside.
7-Methyl-guanosine-5'-triphosphate sodium (m7GTP sodium) V77313 7-Methyl-guanosine-5'-triphosphate sodium (m7GTP sodium) 7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate.
8-(N,N-Dimethylaminomethyl)guanosine V77690 8-(N,N-Dimethylaminomethyl)guanosine 8-(N,N-Dimethylaminomethyl)guanosine is a guanine nucleoside analog.
8-(N-Boc-aminomethyl)guanosine V77691 8-(N-Boc-aminomethyl)guanosine 8-(N-Boc-aminomethyl)guanosine is a guanine nucleoside analog.
8-Aza-2'-beta-C-methylguanosine V81012 8-Aza-2'-beta-C-methylguanosine 8-Aza-2'-beta-C-methylguanosine is an analogue of purine nucleoside.
8-Chloro-2'-deoxy-2'-fluoro inosine V80482 8-Chloro-2'-deoxy-2'-fluoro inosine 8-Chloro-2'-deoxy-2'-fluoro inosine is an analogue of purine nucleoside.
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