|
V70304
|
GPR119 agonist 2
|
1384951-03-4 |
GPR119 agonist 2 (compound 43) is an orally bioactive GPR119 agonist. |
|
V70307
|
GPR139 agonist-2
|
2983118-29-0 |
GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist/activator with EC50 of 24.7 nM. |
|
V75413
|
GPR35 agonist 3
|
123021-85-2 |
GPR35 agonist 3 is a synthetic GPR35 agonist/activator with EC50 of 1.4 μM. |
|
V75412
|
GPR35 agonist 5
|
2226201-24-5 |
GPR35 agonist 5 (3,5-dinitro-bisphenol A; compound 6) is a weak GPR35 agonist. |
|
V75411
|
GPR4 antagonist 1
|
1197879-16-5 |
GPR4 antagonist 1 is an antagonist of GPR4 with IC50 of 189 nM. |
|
V79955
|
GPR55 agonist 3
|
|
GPR55 agonist 3 (Compound 26) is a GPR55 agonist (EC50= 0.239 nM, 1.76 nM for hGPR55 and rGPR55, respectively). |
|
V80068
|
GPR55 agonist 4
|
|
GPR55 agonist 4 (Compound 28) is a GPR55 agonist (EC50= 131 nM, 1.41 nM for hGPR55 and rGPR55). |
|
V75406
|
GPR81 agonist 2
|
1143024-28-5 |
GPR81 agonist 2 (compound 1) is a potent GPR81 agonist/activator with EC50s of 0.023 and 0.123 µM for hGPR81 and hGPR109A respectively. |
|
V75420
|
GPR84 antagonist 1
|
2762180-28-7 |
GPR84 antagonist 1 is a high-affinity, selective competitive antagonist of human GPR84. |
|
V75418
|
GPR84 antagonist 2
|
2244269-74-5 |
GPR84 antagonist 2 (compound 33) is an orally bioactive, selective GPR84 antagonist (IC50=8.95 nM). |
|
V75421
|
GPR84 antagonist 3
|
2815263-05-7 |
GPR84 antagonist 3 (compound 42) is a potent GPR84 (G protein-coupled receptor 84) antagonist. |
|
V75423
|
GPR88 agonist 2
|
2821859-71-4 |
GPR88 agonist 2 (compound 53) is a potent, BBB (blood-brain barrier) permeable (penetrable) GPR88 agonist/activator with EC50 of 14 nM in GPR88 cAMP functional assays. |
|
V85742
|
GPR88 agonist 3
|
2963597-44-4 |
|
|
V75422
|
GPR88-IN-1
|
714265-50-6 |
GPR88-IN-1 is a GPR88 inhibitor that may be utilized in the research/study of central diseases. |
|
V1804
|
GSK1292263
|
1032823-75-8 |
GSK1292263 is a novel and potentGPR119 (G-protein-coupled receptor 119) agonist whichhas potential for the treatment of type 2 diabetes. |
|
V1805
|
GW9508
|
885101-89-3 |
GW9508 is a novel, potent and selective agonist for FFA1 (fatty acid receptor GPR40) with pEC50 of 7.32, and is 100-fold selective against GPR120, it stimulates insulin secretion in a glucose-sensitive manner. |
|
V70560
|
hMCH-1R antagonist 1
|
353487-64-6 |
hMCH-1R antagonist 1 (Compound 30) is a potent and specific human melanin concentrating hormone receptor 1 (hMCHR1) antagonist (inhibitor) with a KB of 3.6 nM. |
|
V70310
|
L-α-lysophosphatidylinositol (Soy) (sodium)
|
796963-91-2 |
L-α-lysophosphatidylinositol Soy sodium is the endogenous ligand of GPR55. |
|
V15704
|
Latanoprost (PHXA41, XA34)
|
130209-82-4 |
Latanoprost (PHXA-41, XA-34) is a novel prostaglandinF2α analogue that lowers the pressure by increasing the outflow of aqueous fluid from the eyes through the uvealsclearal tract. |
|
V75414
|
MS48107
|
2375070-79-2 |
MS48107 is a potent and specific PAM (positive allosteric modulator) of G protein-coupled receptor 68 (GPR68). |