5-HT receptors (Serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems.5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT5, 5-HT6, and 5-HT7 are the types. Both excitatory and inhibitory neurotransmission is mediated by them. The neurotransmitter serotonin, which serves as their inherently ligand, stimulates the serotonin receptors. Numerous neurotransmitters and hormones are released in response to stimulation of the serotonin receptors. Numerous biological and neurological functions, including aggression, anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, and thermoregulation, are influenced by serotonin receptors. Many antidepressants, antipsychotics, anorectics, antiemetics, gastroprokinetic agents, antimigraine agents, hallucinogens, and entactogens are among the pharmaceuticals that target the serotonin receptors.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V102408 | Lesopitron hydrochloride | 132449-88-8 | Lesopilone hydrochloride is a 5-HT receptor agonist with potent anxiolytic effects. |
|
V101176 | Lintopride hydrochloride | 268548-31-8 | Lintopride hydrochloride is a benzamide that is a strong 5HT-4 antagonist and a moderate 5HT-3 antagonist. |
|
V1032 | Lorcaserin HCl | 846589-98-8 | Lorcaserin HCl (Belviq Xr; APD-356; APD356; Lorqess), the hydrochloride salt of Lorcaserin which is a marketed weight-loss drug, is a potent and selective full agonist of human 5-HT2C (serotonin) receptor with Ki of 15 nM. |
|
V93611 | LP-20 hydrochloride | 1386928-34-2 | LP-20 hydrochloride acts as a ligand for the 5-HT7 receptor. |
|
V3191 | LP-211 | 1052147-86-0 | LP-211 is a potent and selective5-HT7receptoragonist with aKiof 0.58 nMat rat cloned 5-HT7 receptors. |
|
V102239 | LPH-5 | 2641630-97-7 | LPH-5 is a selective 5-HT2A receptor agonist (EC50=190 nM). |
|
V3164 | Lu AE58054 (Idalopirdine) | 467459-31-0 | Lu AE58054 (also known as Idalopirdine) is potent and selective antagonist of the 5-HT(6) receptor with Ki value of 0.83 nM. |
|
V2927 | Lu AE58054 hydrochloride | 467458-02-2 | Lu AE58054 hydrochloride (also known as Idalopirdine hydrochloride) is potent and selective antagonist of the 5-HT(6) receptor with Ki value of 0.83 nM. |
|
V87763 | Lurosetron | 128486-54-4 | Lurosetron (GR-87442) is a 6-fluoro analog of Alosetron. |
|
V33553 | LY 344864 | 186544-26-3 | LY-344864 (LY344864) is a novel, potent and selective receptor agonist of 5-HT1F with Ki of 6 nM. |
|
V102447 | LY-272015 | 159730-07-1 | LY-272015 is an orally active, specific 5-HT2B receptor antagonist. |
|
V4839 | LY-344864 HCl | 1217756-94-9 | LY-344864 HCl, the hydrochloride salt of LY344864, is a novel, potent and selective receptor agonist of 5-HT1F with Ki of 6 nM. |
|
V71152 | LY266097 hydrochloride | 172895-39-5 | LY266097 HCl is a selective 5-HT2B receptor antagonist (inhibitor) with pKi of 7.7, 9.8 and 7.6 for 5-HT2A, 5-HT2B and 5-HT2C respectively. |
|
V0981 | LY310762 | 192927-92-7 | LY310762 (LY-310762; LY 310762) is a potent 5-HT1D serotonin receptor antagonist with important biological activity. |
|
V32168 | LY334370 | 182563-08-2 | LY334370 is a selective 5-HT1F receptor agonist (activator) with Ki of 1.6 nM. |
|
V71180 | m-CPBG hydrochloride (1-(3-Chlorophenyl)biguanide hydrochloride) | 2113-05-5 | m-CPBG (1-(3-Chlorophenyl)biguanide) HCl is a selective 5-HT3 agonist. |
|
V102304 | MCI-225 (dehydratase) | 99487-26-0 | MCI-225 Dehydratase is an oral selective norepinephrine reuptake inhibitor. |
|
V71214 | Melitracen-d6 hydrochloride (melitacen d6 hydrochloride) | 1189648-08-5 | Melitracen-d6 ( HCl) is the deuterated form of Melitracen HCl. |
|
V106608 | meta-Fluoxetine hydrochloride | 79088-29-2 | Fluoxetine hydrochloride is an isomer of fluoxetine hydrochloride. |
|
V105404 | Methamnetamine hydrochloride | 2748623-12-1 | Methamphetamine (PAL-1046) hydrochloride is an amphetamine-based psychoactive substance that causes an excess release of serotonin. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
