5-HT receptors (Serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems.5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT5, 5-HT6, and 5-HT7 are the types. Both excitatory and inhibitory neurotransmission is mediated by them. The neurotransmitter serotonin, which serves as their inherently ligand, stimulates the serotonin receptors. Numerous neurotransmitters and hormones are released in response to stimulation of the serotonin receptors. Numerous biological and neurological functions, including aggression, anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, and thermoregulation, are influenced by serotonin receptors. Many antidepressants, antipsychotics, anorectics, antiemetics, gastroprokinetic agents, antimigraine agents, hallucinogens, and entactogens are among the pharmaceuticals that target the serotonin receptors.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V103901 | 5-HT7R antagonist 2 | 1448808-50-1 | 5-HT7R antagonist 2 (compound 4h) is a 5-HT7R antagonist that antagonizes G protein and β-arrestin signaling pathways with Ki values of 67 nM and IC50 values of 2.59 μM and 39.57 μM for 5-HT7R in cAMP and Tango assays, respectively. |
|
V103696 | 5-HT7R antagonist 3 | 1887043-58-4 | 5-HT7R antagonist 3 (compound 6.4) is a selective 5-HT7R antagonist with a Ki of 8 nM, while the Kis for D2R, 5-HT1AR, and 5-HT2AR are 511 nM, 8930 nM, and 5786 nM, respectively. |
|
V92297 | 5-HTQ chloride | 40581-89-3 | 5-HTQ chloride is an indole alkaloid isolated from the skin secretions of the Australian golden bell frog, Litoria aurea. |
|
V103252 | 5-IAI hydrochloride | 1782044-60-3 | 5-IAI hydrochloride is a psychoactive analog of p-iodine. |
|
V105072 | 5-MeO-MET | 16977-53-0 | 5-MeO-MET (5-methoxy-N-methyl-N-ethyltryptamine) is a 5-methoxytryptamine compound. |
|
V107562 | 5-MeO-pyr-T | 3949-14-2 | 5-MeO-pyr-T (5-methoxypyrrolidinyltryptamine) is a 5-HT1AR agonist with Ki values of 0.577 and 373 μM for 5-HT1AR and 5-HT2AR, respectively. |
|
V0993 | Serotonin HCl | 153-98-0 | Serotonin HCl (5-HT HCl; 5-Hydroxytryptamine), the hydrochloride salt of Serotonin, is an endogenous monoamine neurotransmitter found in the brain and also an endogenous agonist of 5-HT receptor. |
|
V101287 | 5HT6-ligand-2 | 5HT6-ligand-2 (Compound 15) is a potent 5-HT6 inhibitor with Ki values of 3.4 and 15 nM for 5-HT6 and SERT, respectively. | |
|
V104679 | 6-Fluoro-N,N-diethyltryptamine | 2836-69-3 | 6-Fluoro-N,N-diethyltryptamine (6-F-DET) has affinity for 5-HT2A receptors. |
|
V71223 | 7-Desmethyl-agomelatine-d3 (7-desmethyl agomelatine impurity 5-d3) | 2749427-92-5 | 7-Desmethyl-agomelatine-d3 is the deuterium labelled form of 7-Desmethyl-agomelatine. |
|
V104779 | 7-Methyl DMT | 65882-39-5 | 7-Methyl DMT (7-TMT) is a 5-HT2 receptor agonist. |
|
V107581 | 8-Hydroxy mirtazapine | 102335-57-9 | 8-Hydroxymirtazapine is a metabolite of the antidepressant drug mirtazapine, which is produced by mirtazapine under the action of cytochrome P450 (CYP) isozyme CYP2D6. |
|
V2790 | 8-OH-DPAT | 78950-78-4 | 8-OH-DPAT (also known as 8-Hydroxy-DPAT) is a classic, potent and selective agonist of 5-HT1A with the potential to be used for sleep disorders. |
|
V95000 | AAZ-A 154 | 2481740-94-5 | AAZ-A 154 is a selective, competitive and non-psychedelic 5-HT2AR antagonist. |
|
V95341 | AAZ-A 154 benzoate | 2930845-92-2 | AAZ-A 154 benzoate is a selective, competitive and non-psychedelic 5-HT2AR antagonist. |
|
V95443 | AAZ-A 154 hydrobromide | 2930845-96-6 | AAZ-A 154 hydrobromide is a selective, competitive and non-psychedelic 5-HT2AR antagonist. |
|
V95099 | AAZ-A 154 hydrochloride | 2930845-89-7 | AAZ-A 154 hydrochloride is a selective, competitive and non-psychedelic 5-HT2AR antagonist. |
|
V95209 | AAZ-A 154 mesylate | 2930846-03-8 | AAZ-A 154 mesylate is a selective, competitive and non-psychedelic 5-HT2AR antagonist. |
|
V104690 | Aeruginascin | 114264-95-8 | Aeruginosa is an indole derivative and tryptophan amine that can be extracted from Pseudomonas aeruginosa. |
|
V104227 | AGH-107 | 2172907-10-5 | AGH-107 is a highly selective, blood-brain permeable 5-HT7 receptor agonist with a Ki value of 6 nM and an EC50 value of 19 nM. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
