The three G-protein-coupled cannabinoid receptor subtypes currently recognized are central (CB1), peripheral (CB2), and GPR55. The majority of CB1 receptors are found at central and peripheral nerve terminals. CB2 receptors are mainly found in immune cells and non-neuronal tissues where they regulate cytokine release and cell migration. According to recent reports, the CNS may also express CB2 receptors. Non-CB1/CB2 receptors known as GPR55 show affinity for endogenous, botanical, and synthetic cannabinoids. Anandamide and 2-arachidonylglycerol are examples of endogenous ligands for cannabinoid receptors.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V71597 | (R)-(+)-Linoleyl-1'-Hydroxy-2'-Propylamide | 220556-74-1 | (R)-(+)-Linoleyl-1'-Hydroxy-2'-Propylamide (Compound 19) is an analog of the endocannabinoid receptor ligand Anandamide. | |
V71551 | (R)-Monlunabant ((R)-MRI-1891) | 2765579-76-6 | (R)-Monlunabant ((R)-MRI-1891) is a CB1 receptor modulator utilized in study/research of obesity and metabolic diseases. | |
V71573 | 15(S)-HETE Ethanolamide | 161744-53-2 | 15(S)-HETE Ethanolamide is an analog of cannabinoids that works on the CB1 receptor (Ki 600 nM). | |
V86543 | 2-Linoleoyl glycerol | 3443-82-1 | 2-Linoleoyl glycerol (2-Monolinolein; 2-Monolinoleoylglycerol) is a monoglyceride that is an antagonist and partial agonist of the type 1 cannabinoid CB1 receptor. | |
V71592 | 2-Palmitoylglycerol (2-Palm-Gl) | 23470-00-0 | 2-Palmitoylglycerol (2-Palm-Gl) is an analog of 2-arachidonoylglycerol (2-AG) and a moderate cannabinoid receptor CB1 agonist. | |
V5397 | 2-Arachidonoylglycerol | 53847-30-6 | 2-Arachidonoylglycerol, an endocannabinoid compound, is an endogenous agonist for the cannabinoid (CB1) receptor in the central nervous system. | |
V86548 | AChE/BChE-IN-18 | AChE/BChE-IN-18 (Compound 4g) is an AChE/BchE dual inhibitor with an IC50 value of 0.315 μM for AchE. | ||
V71582 | AEF0117 | 1610878-71-1 | AEF0117 is a signaling-specific inhibitor of cannabinoid receptor 1 (CB1-SSi). | |
V1516 | AM1241 | 444912-48-5 | AM-1241 (AM1241; AM 1241), anaminoalkylindole analog, is a novel, potent and selective cannabinoid (CB2) receptor agonist with potential analgesic effects (pain-killing). | |
V1517 | AM251 | 183232-66-8 | AM251 (AM-251; AM 251) is a novel, potent and selective cannabinoid (CB) receptor antagonist with potential anti-obesity effect. | |
V71584 | AM841 | 871978-21-1 | AM841 is a high-affinity electrophilic ligand. | |
V71568 | AM8936 | 2820337-96-8 | AM8936 is a balanced and potent agonist of cannabinoid receptor type 1 (CB1) (EC50 for rCB1 and hCB1 of 8.6 and 1.4 nM, respectively). | |
V86545 | Amauromine | 88360-87-6 | Amauromine is a peripherally selective cannabinoid receptor type 1 (CB1) receptor antagonist with Ki and Kb values of 178 nM and 66.6 nM, respectively. | |
V71590 | ANEB-001 | 791848-71-0 | ANEB-001 is an orally bioactive CB1 inhibitor used to study acute cannabinoid intoxication. | |
V86564 | Arachidonoyl-N,N-dimethyl amide | 45280-17-9 | Arachidonoyl-N,N-dimethyl amide (Arachidonic acid-N,N-dimethyl amide) is an endocannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. | |
V71557 | Arachidonylcyclopropylamide (ACPA) | 229021-64-1 | Arachidonylcyclopropylamide (ACPA) is a potent and specific CB1 receptor agonist. | |
V7326 | AZD-1940 | 881413-29-2 | AZD1940 is an orally bioactive, high-affinity cannabinoid CB1/CB2 receptor agonist (activator) with pKis of 7.93 and 9.06 for CB1R and CB2R, respectively, and can be used for pain relief research. | |
V3360 | Bay 59-3074 | 406205-74-1 | Bay 59-3074 is a novel, potent, orally active and selective cannabinoid CB1/CB2 receptor partial agonist with Ki values of 48.3 and 45.5 nM at human CB1 and CB2 receptors respectively. | |
V3361 | BAY-38-7271 | 212188-60-8 | BAY-38-7271 is novel, potent, highly selective cannabinoid receptor agonist with the potential for the treatment of traumatic brain injury. | |
V78516 | Boc-MIF-1-Am | Boc-MIF-1-Am (compound 2) is a human dopamine D2 receptor enhancer (EC50=17.82 nM) and a bioconjugate of melanostatin (MIF-1) and amantadine. |