The acetylcholine receptors known as mAChRs (muscarinic acetylcholine receptors) are found in the cell membranes of some neurons and other cells. The primary end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system is one of their many functions. Because they are more sensitive to muscarine than to nicotine, mAChRs are so named. Nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also significant in the autonomic nervous system, are their counterparts. Numerous medications and other substances, such as scopolamine and pilocarpine, act as selective agonists or antagonists on these two different receptors. The brain and the autonomic ganglia are both rich sources of the neurotransmitter acetylcholine (ACh).
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V50968 | Muscarine chloride | 2936-25-6 | (±)-Muscarinic acid chloride is the racemate of muscarinic acid chloride. |
|
V70515 | Muscarine iodide ((+)-Muscarine iodide) | 24570-49-8 | Muscarine ((+)-Muscarine) iodide is a toxin that stimulates the parasympathetic nervous system. |
|
V86287 | Muscarine tosylate ((+)-Muscarine tosylate) | 82083-43-0 | |
|
V80856 | Muscarine-d9 iodide ((+)-Muscarine-d9 (iodide)) | Muscarine-d9 (iodide) is the deuterated form of Muscarine iodide. | |
|
V80857 | Muscarinic toxin 7 | Muscarinic toxin 7 is a bioactive peptide toxin with selective and noncompetitive antagonism at the muscarinic M1 receptor. | |
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V70511 | N-Demethyl MK-6884 | 2102194-36-3 | N-Demethyl MK-6884 (compound 34) is a potent allosteric modulator of M4 mAChR. |
|
V86288 | N-Desethyloxybutynin hydrochloride | 81039-77-2 | |
|
V60110 | Norarecoline hydrochloride | 6197-39-3 | Guvacoline hydrochloride is a pyridine alkaloid that can function as a weak full agonist of ileal and atrial muscarinic receptors. |
|
V0462 | Norbenzetimide | 19315-71-0 | Nor-benzetimide is the major metabolite of benzetimide. |
|
V5276 | Norclozapine (ACP-104) | 6104-71-8 | Norclozapine (ACP-104; NDMC; ACP104; N-Desmethylclozapine) is a major active metabolite of the atypical antipsychotic drug clozapine. |
|
V30659 | Oxotremorine M iodide | 3854-04-4 | Oxotremorine M iodide is a novel, potent and selective muscarinic acetylcholine receptor (mAChR) agonist. |
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V70502 | Oxotremorine sesquifumarate | 17360-35-9 | Oxotremorine sesquifumarate is a mAChR agonist with stronger activation of M2 and may be utilized in neurological research. |
|
V70553 | Parapenzolate bromide | 5634-41-3 | Parapenzolate bromide, an antispasmodic agent, is an orally bioactive mAChR antagonist. |
|
V70509 | PD 102807 | 23062-91-1 | PD 102807 is an M4 muscarinic receptor antagonist (inhibitor) with IC50 of 90.7 nM. |
|
V70550 | PF-4348235 (β2AR/M-receptor agonist-2) | 1017857-38-3 | β2AR/M-receptor agonist-2 (compound 15) is a muscarinic antagonist and β2-adrenoceptor agonist (MABA). |
|
V32729 | Pilocarpine nitrate | 148-72-1 | Pilocarpine nitrate, the nitrate salt of pilocarpine, is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. |
|
V22201 | Piperidolate | 82-98-4 | Piperidolate is a tertiary amine antimuscarinic. |
|
V3358 | Pirmenol (Cl-845) | 68252-19-7 | Pirmenol (Cl-845) is a potent antiarrhythmic agent that inhibits muscarinic acetylcholine receptor-operated K+ current in the guinea pig heart. |
|
V29911 | Pirmenol hydrochloride | 61477-94-9 | Pirmenol HCl (Cl-845)is a potent antiarrhythmic agent that inhibits muscarinic acetylcholine receptor-operated K+ current in the guinea pig heart. |
|
V70522 | Propantheline-d3 bromide (Propantheline-d3 bromide) | 64717-35-7 | Propantheline-d3 (bromide) is the deuterated form of Propantheline bromide. |
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