Prostaglandin receptor, a sub-family of cell surface seven-transmembrane receptors, are the G-protein-coupled receptors.Ten distinct prostaglandin receptors on different cell types are currently known. G-protein-coupled receptors are a subclass of cell surface seven-transmembrane receptors that prostaglandins bind to. The following are the names of these receptors: FP-FP, IP1-2-IP1, IP2 receptors, TP-TP receptor, EP1-4-EP1, EP2, EP3, and EP4 receptors. A class of lipid molecules known as prostaglandins, which are produced enzymatically from fatty acids and resemble hormones, play vital roles in the bodies of animals. Ten distinct prostaglandin receptors on different cell types are currently known.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V2071 | Bimatoprost (AGN 192024) | 155206-00-1 | Bimatoprost (AGN-192024; Latisse; Lumigan; Bimatoprostum; AGN192024) is a potent FP (Prostaglandin F) receptor agonist and a prostaglandin analog used topically as eye drops to control the progression of glaucoma and in the management of ocular hypertension. |
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V74466 | Bimatoprost grenod (NCX 470) | 1194396-71-8 | Bimatoprost grenod (NCX 470) is a second generation NO donor prostaglandin analog. |
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V78815 | Bimatoprost-d4 (AGN 192024-d4) | Bimatoprost-d4 is the deuterium labelled form of Bimatoprost. | |
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V67556 | Butaprost | 69685-22-9 | Butaprost is a selective prostaglandin E receptor (EP2) agonist/activator with EC50 of 33 nM and a Ki of 2.4 μM for the murine EP2 receptor. |
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V86071 | Camonagrel | 105920-77-2 | |
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V73508 | Canniprene | 70677-47-3 | Canniprene is a prenylated bibenzyl unique to cannabis and is responsible for 5-lipoxygenase (5-LO) activity (IC50=0.4 μM) and cyclooxygenase/microsomal prostaglandin E2 synthase (PGE2; Effective inhibitor (antagonist) with IC50=10 μM). |
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V4963 | CAY10471 Racemate | 844639-57-2 | CAY10471 Racemate (also known as TM-30089 Racemate) is a novel, potent and highly selective prostaglandin D2 receptor CRTH2 antagonist with a Kiof 0.6 nM for hCRTH2, it is selective over human thromboxane A2 receptor TP (Ki, >10000 nM) or PGD2 receptor DP (Ki, 1200 nM). |
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V74461 | CAY10580 | 64054-40-6 | CAY10580 is a potent and specific prostaglandin EP4 receptor (EP4) agonist (Ki=35 nM). |
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V18401 | CJ-042794 (CJ-042794) | 847728-01-2 | CJ-042794 (CJ-042794) is a a novel, potent, and selective prostaglandin EP(4) receptor antagonist, with a mean pKi of 8.5, a binding affinity that was at least 200-fold more selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3). |
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V2991 | CP-544326 | 752187-80-7 | Taprenepag (formerly known as CP-544326) is a potent and selective agonist of EP2 (prostaglandin EP receptor 2) with IC50 of 10nM and EC50 of 2.8nM. |
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V19993 | Dinoprost Tromethamine | 38562-01-5 | Dinoprost Tromethamine (Prostaglandin F2alpha; PGF2α THAM; Prostaglandin F2α THAM) is apotent,naturally occurring andorally bioactiveprostaglandin that acts as aprostaglandin F (PGF) receptor (FP receptor)agonist withoxytocic, luteolytic, and abortifacient activities. |
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V13210 | E7046 | 1369489-71-3 | E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) receptor EP4. |
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V74472 | EP2 receptor antagonist-1 | 848920-08-1 | EP2 receptor antagonist-1 (Compound 1) is a potent, reversible and agonist-dependent allosteric prostaglandin EP2 receptor antagonist. |
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V74462 | EP2 receptor antagonist-2 | 615273-95-5 | EP2 receptor antagonist-2 (CID891729) is an EP2 receptor antagonist. |
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V74457 | EP3 antagonist 4 | 2408297-80-1 | EP3 antagonist 4 (Compound 28) is an EP3 antagonist (inhibitor) with a Ki of 2 nM for hEP. |
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V84759 | EP3 antagonist 5 | 499147-44-3 | |
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V85191 | EP3 antagonist 6 | 499149-94-9 | |
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V85194 | EP3 antagonist 7 | 740850-59-3 | |
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V74475 | EP4 receptor antagonist 2 | 1965316-82-8 | EP4 receptor antagonist 2 (compound 2-13) is a potent EP4 receptor agonist/activator with IC50 of 7.8 nM. |
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V74489 | EP4 receptor antagonist 3 | 1207954-34-4 | EP4 receptor antagonist 3 is a potent EP4 receptor antagonist, Example 3, derived from the patented product WO2010019796 A1. |
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