Prostaglandin receptor, a sub-family of cell surface seven-transmembrane receptors, are the G-protein-coupled receptors.Ten distinct prostaglandin receptors on different cell types are currently known. G-protein-coupled receptors are a subclass of cell surface seven-transmembrane receptors that prostaglandins bind to. The following are the names of these receptors: FP-FP, IP1-2-IP1, IP2 receptors, TP-TP receptor, EP1-4-EP1, EP2, EP3, and EP4 receptors. A class of lipid molecules known as prostaglandins, which are produced enzymatically from fatty acids and resemble hormones, play vital roles in the bodies of animals. Ten distinct prostaglandin receptors on different cell types are currently known.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V85804 | EP4 receptor antagonist 5 | ||
|
V74479 | EP4-IN-1 | 2455480-28-9 | EP4-IN-1 is a potent prostaglandin EP4 receptor blocker/inhibitor. |
|
V67695 | Epi-cryptoacetalide (Epi-cryptoacetalide) | 132152-57-9 | Epi-cryptoacetalide is a natural diterpenoid. |
|
V20762 | Ethamsylate | 2624-44-4 | Ethamsylate (E-141; MD-141; Aglumin; Altodor; Eselin), a benzenesulfonate analogue, is an antihemorrhagic drug (haemostatic drug) which works by increasing resistance in the endothelium of capillaries and promoting platelet adhesion. |
|
V2855 | Evatanepag (CP-533536) | 223488-57-1 | Evatanepag (formerly known as CP-533536; CP-533536 free acid) is a novel, potent and selective agonist of EP2 receptor prostaglandin E2 (PGE2). |
|
V3987 | FEVIPIPRANT | 872365-14-5 | Fevipiprant (formerly known as NVP-QAW039 or QAW039) is a novel, selective, potent, oral active and reversible competitive CRTh2 (chemoattractant receptor-homologous molecules expressed on T-helper type 2) antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood. |
|
V11725 | Genz-123346 | 491833-30-8 | Genz-123346 is a novel, potent and selective glucosylceramide synthase inhibitor with potential anticancer activity. |
|
V3983 | GRAPIPRANT | 415903-37-6 | Grapiprant (formerly known as CJ-023,423, RQ-00000007, or AAT-007) is a selective and potent EP4 receptor antagonist. |
|
V4931 | GW627368 | 439288-66-1 | GW627368 (also known as GW-627368; GW-627368X) is a novel, orally bioavailable, potent and selective competitive antagonist of prostanoid EP4 receptor with anticancer activity. |
|
V74491 | I-SAP | 133538-58-6 | I-SAP is a radioactive TXA2/PGH2 receptor antagonist. |
|
V8868 | Iloprost (Ciloprost; ZK-36374) | 78919-13-8 | Iloprost (Ciloprost; ZK-36374; Trade names: Ventavis, Ilomedine), a novel potent synthetic analog of prostacyclin PGI2, is an approved drug used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are constricted and blood can't flow to the tissues. |
|
V74468 | Iloprost-d4 (Iloprost d4) | 1035094-10-0 | Iloprost-d4 is the deuterium labelled form of Iloprost. |
|
V74492 | KMN-80 | 1628759-75-0 | KMN-80, an analogue of PGE1, is a selective agonist of EP4 receptor, with IC50 and Ki of 3 nM and 2.35 nM respectively. |
|
V4363 | LAROPIPRANT | 571170-77-9 | Laropiprant (aslo known as MK-0524; Cordaptive) is a novel, potent, selective DP [prostaglandin D2 (PGD2) receptor (DP)] receptor antagonist with Ki values of 0.57 nM and 2.95 nM for DP receptor and TP Receptor, respectively. |
|
V80538 | Latanoprost-d4 (PHXA41-d4) | Latanoprost-d4 is the deuterium labelled form of Latanoprost. | |
|
V5017 | Misoprostol | 59122-46-2 | Misoprostol (formerly known as SC29333), a synthetic prostaglandin E1 (PGE1) analog, is a medication used to treat missed miscarriage, to induce labor, and to induce abortion. |
|
V4292 | MK-2894 | 1006036-87-8 | MK-2894 is a novel, potent and selective antagonist of prostaglandin E2 subtype 4 receptor (PGE2). |
|
V4293 | MK-2894 sodium | 1006036-88-9 | MK-2894 sodium is a novel, potent and selective antagonist of prostaglandin E2 subtype 4 receptor (PGE2). |
|
V4288 | MK-447 | 58456-91-0 | MK-447 (MK447) is a novel and potent free radical scavenger. |
|
V4314 | MK-7246 | 1218918-62-7 | MK-7246 is a novel, potent and selective CRTH2 antagonist with Ki of 2.5±0.5 nM. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
