Prostaglandin receptor, a sub-family of cell surface seven-transmembrane receptors, are the G-protein-coupled receptors.Ten distinct prostaglandin receptors on different cell types are currently known. G-protein-coupled receptors are a subclass of cell surface seven-transmembrane receptors that prostaglandins bind to. The following are the names of these receptors: FP-FP, IP1-2-IP1, IP2 receptors, TP-TP receptor, EP1-4-EP1, EP2, EP3, and EP4 receptors. A class of lipid molecules known as prostaglandins, which are produced enzymatically from fatty acids and resemble hormones, play vital roles in the bodies of animals. Ten distinct prostaglandin receptors on different cell types are currently known.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V74497 | MK-7246 S enantiomer | 2310135-53-4 | MK-7246 S enantiomer is the less active enantiomer of MK-7246. |
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V5217 | MRE-269 (ACT-333679) | 475085-57-5 | MRE-269 (also known as MRE269; ACT-333679), an active metabolite of selexipag (also known as NS-304), is a novel, potent along-acting and selective IP (prostaglandin I2) receptor agonist. |
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V74486 | MRE-269-d7 (ACT-333679-d7) | 1265295-20-2 | MRE-269-d7 is the deuterium labelled form of MRE-269 . |
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V83606 | N-Cyclopropyl bimatoprost | 1138395-12-6 | |
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V37610 | NTP42 | 2055599-51-2 | NTP42 is a novel thromboxane A2 (TXA2) receptor antagonist with an IC50 of 3.278 nM for antagonizing T prostanoid receptor (TP)- mediated [Ca2+] mobilization following stimulation of cells with the alternative TP agonist U46609. |
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V79159 | NXT-10796 | NXT-10796 is an orally bioactive entero-restricted EP4 receptor agonist (activator). | |
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V76681 | ONO-8711 dicyclohexylamine | ONO-8711 dicyclohexylamine is a potent and specific competitive EP1 antagonist (inhibitor) with Kis of 0.6 nM and 1.7 nM for human and mouse EP1, respectively. | |
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V74477 | ONO-8713 | 459411-08-6 | ONO-8713 is a selective prostaglandin E receptor subtype EP1 antagonist. |
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V4681 | ONO-AE3-208 | 402473-54-5 | ONO-AE3-208 is a novel and potent EP4 antagonist with Ki of 1.3 nM. |
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V21605 | Ozagrel Sodium | 189224-26-8 | Ozagrel Sodium (formerly known as KCT-0809 and Cataclot) is the sodium salt of Ozagrel(also known as OKY-046) which is a potent and selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, it is used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia. |
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V74465 | PDC31 (THG113.31; ILGHXDYK) | 634586-40-6 | PDC31 (THG113.31; ILGHXDYK) is an allosteric and noncompetitive inhibitor of the FP Prostaglandin Receptor. |
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V74467 | Pexopiprant | 932708-14-0 | Pexopiprant is an oral antagonist of prostaglandin D2 receptor 2 (DP2) with Ki < 100nM. |
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V1881 | PF-04418948 | 1078166-57-0 | PF-04418948 is a novel, potent and selective prostaglandin EP2 receptor antagonist. |
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V7294 | PGD2-IN-1 | 885066-67-1 | PGD2-IN-1 is a DP receptor blocker (antagonist), disclosed in patent WO 2006044732 A2, example compound 15 (d), with IC50 of 0.3 nM. |
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V86150 | PGN-9856 | 863704-91-0 | |
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V27653 | Pizuglanstat | 1244967-98-3 | Pizuglanstat is a novel and potent prostaglandin D synthase inhibitor with the potential forDuchenne muscular dystrophy (DMD). |
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V74484 | Prostaglandin D3 (PGD3) | 71902-47-1 | Prostaglandin D3 (PGD3) is a prostaglandin compound that works as an inhibitor (blocker/antagonist) of platelet aggregation and a modulator of autonomic neurotransmission in humans. |
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V4216 | Ramatroban | 116649-85-5 | Ramatroban is a novel, potent and selectiveantagonist of thromboxane A2(TxA2) with an IC50of 14 nM. |
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V3669 | RO1138452 | 221529-58-4 | RO1138452 is a novel, potent and selective antagonist of the IP (prostacyclin) receptor. |
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V74460 | SC 51089 free base | 146033-03-6 | SC 51089 free base is a selective prostaglandin receptor EP1 antagonist (inhibitor) with Kis of 1.3, 11.2, 17.5 and 61.1 μM for EP1, TP, EP3 and FP receptors respectively. |
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