Prostaglandin receptor, a sub-family of cell surface seven-transmembrane receptors, are the G-protein-coupled receptors.Ten distinct prostaglandin receptors on different cell types are currently known. G-protein-coupled receptors are a subclass of cell surface seven-transmembrane receptors that prostaglandins bind to. The following are the names of these receptors: FP-FP, IP1-2-IP1, IP2 receptors, TP-TP receptor, EP1-4-EP1, EP2, EP3, and EP4 receptors. A class of lipid molecules known as prostaglandins, which are produced enzymatically from fatty acids and resemble hormones, play vital roles in the bodies of animals. Ten distinct prostaglandin receptors on different cell types are currently known.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V74464 | (+)-Fluprostenol | 54276-17-4 | (+)-Fluprostenol is a potent agonist of PTGER2. |
|
V74493 | (+)-Oxypeucedanin methanolate | 52939-12-5 | (+)-Oxypeucedanin methanolate (compound 9) is a naturally occurring compound that can inhibit prostaglandin E2 production. |
|
V74496 | (8-epi)-BW 245C | 65705-83-1 | (8-epi)-BW 245C is the C-8 diastereomer of BW 245C. |
|
V74478 | (S)-Butaprost free acid | 433219-55-7 | (S)-Butaprost (free acid) is a potent and selective EP2 receptor agonist (activator). |
|
V74485 | 11-Deoxy Prostaglandin E2 | 35536-53-9 | 11-Deoxy Prostaglandin E2 is an EP4 selective agonist/activator with EC50 of 0.66 nM. |
|
V84325 | 12(S)-HPEPE | 103239-14-1 | |
|
V83666 | 13,14-Dihydro-15-keto prostaglandin D2 (DK-PGD2; 15-Oxo-13,14-dihydro-PGD2; 13,14-Dihydro-15-keto-PGD2) | 59894-07-4 | |
|
V84195 | 15(S)-HpEPE | 125992-60-1 | |
|
V74482 | 15-Keto latanoprost | 135646-98-9 | 15-Keto latanoprost is a metabolite of Latanoprost, an intraocular pressure-lowering agent. |
|
V74488 | 19(S)-HETE | 115461-40-0 | 19(S)-HETE is an arachidonic acid metabolite produced by cytochrome P450 enzymes. |
|
V74458 | 1a,1b-Dihomo prostaglandin E1 (1a,1b-Dihomo PGE1) | 23452-98-4 | 1a,1b-Dihomo prostaglandin E1 (1a,1b-Dihomo PGE1) is a class of prostaglandin compounds. |
|
V10518 | AH6809 | 33458-93-4 | AH6809 (AH-6809) is a novel and potent DP/EP prostanoid receptor antagonist with a Ki of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively, and with a Ki of 350 nM for mouse EP2 receptor. |
|
V2425 | Alprostadil (PGE1; Prostaglandin-E1) | 745-65-3 | Alprostadil (also known as Prostaglandin-E1) is a naturally occurring prostaglandin and a potent vasodilator used in the treatment of infants with congenital heart defects to maintain the patency of the ductus arteriosus until palliative or corrective surgery can be performed. |
|
V3450 | AMG-009 | 1027847-67-1 | AMG-009 is a novel, potent, orally bioactive, small molecule antagonist of prostaglandin D2, with IC50 of 3 nM and 12 nM for CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells) and DP (D prostanoid) receptors, respectively. |
|
V74494 | AMX12006 | 2639775-01-0 | AMX12006 is a specific and orally bioactive EP4 antagonist (inhibitor) with IC50 of 4.3 nM. |
|
V74463 | AZ12672857 | 945396-55-4 | AZ12672857 is an orally bioactive inhibitor of EphB4 (IC50=1.3 nM) and Src kinase. |
|
V74474 | BAY-6672 | 2247517-53-7 | BAY-6672 is a potent and specific human prostaglandin F (FP) receptor blocker (antagonist) with IC50 of 11 nM. |
|
V74476 | BAY-6672 hydrochloride | 2247520-31-4 | BAY-6672 HCl is a potent and specific human prostaglandin F (FP) receptor blocker (antagonist) with IC50 of 11 nM. |
|
V74469 | BGC-20-1531 free base (PGN 1531 free base) | 736183-35-0 | BGC-20-1531 (PGN 1531) free base is a potent and specific prostaglandin EP4 receptor antagonist (inhibitor) with a pKB value of 7.6. |
|
V84541 | Bima SA (Bimatoprost serinol amide) | 1175838-84-2 |
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