A family of enzymes known as monoamine oxidases (MAO) catalyzes the oxidation of monoamines. In the majority of the body's cell types, they are discovered bound to the mitochondria's outer membrane. They are a member of the flavin-containing amine oxidoreductase protein family. The oxidative deamination of monoamines is catalyzed by monoamine oxidases. By using oxygen to remove an amine group from a molecule, the resulting aldehyde and ammonia are produced.Flavoproteins are monoamine oxidases because they have the cofactor FAD covalently bound to them. MAO dysfunction is thought to be the cause of a number of psychiatric and neurological disorders due to the critical part MAOs play in the inactivation of neurotransmitters. While MAO-B inhibitors are used alone or in combination to treat Alzheimer's and Parkinson's diseases, MAO-A inhibitors have antidepressant and antianxiety properties.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V70654 | hMAO-B-IN-5 | 358343-63-2 | hMAO-B-IN-5(B15) is a specific and reversible inhibitor of human monoamine oxidase hMAO-B with IC50 of 0.12 μM. |
|
V85813 | hMAO-B-IN-6 | 2764830-43-3 | |
|
V85425 | hMAO-B-IN-7 | 2955577-14-5 | |
|
V70661 | hMAO-B/MB-COMT-IN-1 | 254974-70-4 | hMAO-B/MB-COMT-IN-1 is a dual MAO-B/MB-COMT inhibitor (IC50s: hMAO-B is 2.5 μM, MB-COMT is 3.84 μM). |
|
V70679 | Homopterocarpin ((-)-Homopterocarpin; 3,9-Dimethoxypterocarpan) | 606-91-7 | Homopterocarpin is an isoflavone that can be extracted from Pterocarpus erinaceus. |
|
V70658 | Hydroxylamine-d3 hydrochloride (hydroxylamine hydrochloride-d3; hydroxylamine hydrochloride-d3) | 15588-23-5 | Hydroxylamine-d3 ( HCl) is the deuterated form of Hydroxyamine HCl. |
|
V20851 | Hypericin (SGX301) | 548-04-9 | Hypericin(also known as SGX301), is a novel, first-in-class photodynamic therapy using a potent photosensitizer, synthetic hypericin, that is topically applied and activated by safe visible fluorescent light. |
|
V80226 | IHC3 | IHC3 is a competitive and reversible inhibitor of MAO-B (IC50= 1.672 μM). | |
|
V3149 | Iproniazid | 54-92-2 | Iproniazid (brand/other names of Marsilid, Rivivol, Euphozid, Iprazid, Ipronid, Ipronin) is a non-selective, and irreversiblemonoamine oxidase inhibitor (MAOI). |
|
V22802 | J147 | 1146963-51-0 | J147 is a potent neuroprotective and neurotrophic compound. |
|
V84211 | J147 | 1807913-16-1 | |
|
V70650 | Kynuramine dihydrobromide | 304-47-2 | Kynuramine diHBr is an endogenous amine and a fluorescent substrate for plasma amine oxidase. |
|
V70642 | Kynuramine dihydrochloride | 36681-58-0 | Kynuramine is an endogenous amine and a fluorescent substrate and probe for plasma amine oxidase. |
|
V70692 | Ladostigil (TV-3326) | 209394-27-4 | Ladostigil (TV-3326) is an orally bioavailable dual (bifunctional) inhibitor of cholinesterase (cholinesterase) and brain-selective monoamine oxidase (MAO). |
|
V70691 | Ladostigil hemitartrate (TV-3326 hemitartrate) | 209394-46-7 | Ladostigil (TV-3326) hemitartrate is an orally bioavailable dual (bifunctional) inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO). |
|
V70694 | Ladostigil hydrochloride (TV-3326 hydrochloride) | 209394-18-3 | Ladostigil (TV-3326) HCl is an orally bioavailable dual (bifunctional) inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO). |
|
V4155 | Lazabemide | 103878-84-8 | Lazabemide (also known as Ro 19-6327; proposed trade namesPakio,Tempium) is novel, potent, selective, reversible monoamine oxidase B (MAO-B) inhibitor with IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively. |
|
V70695 | Lazabemide hydrochloride (Ro 19-6327 hydrochloride) | 103878-83-7 | Lazabemide HCl (Ro 19-6327 HCl) is a selective and reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM), but has low activity against MAO-A (IC50>100 μM). |
|
V41859 | LOX-IN-3 dihydrochloride | 2409964-23-2 | LOX-IN-3 (PXS5505; PXS-5505) dihydrochloride is a novel and oral inhibitor of lysyl oxidase (LOX)with potential usefulness for treatment of a variety of disorders, e. |
|
V70649 | LOX-IN-3 dihydrochloride monohydrate | 2414974-55-1 | LOX-IN-3 diHCl monohydrate (Compound 33) is an orally bioactive lysyl oxidase (LOX) inhibitor for fibrosis, cancer and angiogenesis research. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
