Hepatitis B virus, also known as HBV or Orthohepadnavirus, is a type of virus that belongs to the Hepadnaviridae family of viruses. Hepatitis B is brought on by the virus HBV. The ground squirrel hepatitis virus, the woodchuck hepatitis virus, and the woolly monkey hepatitis B virus are the other three species that make up the Orthohepadnavirus, of which the hepatitis B virus is the type species. The Hepadnaviridae family includes the genus as a member. Based on antigenic epitopes found on its envelope proteins, HBV is classified into four major serotypes (adr, adw, ayr, ayw), and eight genotypes (A-H) based on the genome's overall nucleotide sequence variation.The genotypes are used to track the evolution and spread of the virus because they have a distinct geographic distribution. The severity of the disease, the progression and propensity for complications, the response to treatment, and perhaps vaccination, are all impacted by genotype differences.
Structure | Cat No. | Product Name | CAS No. | Product Description |
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V52007 | HBV-IN-31 | 2413192-95-5 | HBV (hepatitis B virus)-IN-31 is a potent inhibitor of covalently closed circular DNA (cccDNA). |
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V52006 | HBV-IN-32 | 2413193-04-9 | HBV (hepatitis B virus)-IN-31 is a potent inhibitor of covalently closed circular DNA (cccDNA). |
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V79034 | HBV-IN-33 | HBV (hepatitis B virus)-IN-33 (C-49) is an inhibitor (blocker/antagonist) of HBV (hepatitis B virus) and significantly inhibits HBV (hepatitis B virus) replication in HepAD38, HepG2-HBV (hepatitis B virus)1.3 and HepG2-NTCP cells. | |
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V54179 | HBV-IN-34 | 2716906-45-3 | HBV (hepatitis B virus)-IN-34 (compound 17i) is a potent inhibitor of HBsAg production. |
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V79441 | HBV-IN-35 | HBV (hepatitis B virus)-IN-35 (Compound 88) is an HBV (hepatitis B virus) inhibitor. | |
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V79710 | HBV-IN-36 | HBV (hepatitis B virus)-IN-36 (compound 42) is a potent HBV (hepatitis B virus) inhibitor (IC50=2 μM) with antiviral effect. | |
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V54204 | HBV-IN-37 | 380483-01-2 | HBV (hepatitis B virus)-IN-37 is an HBV (hepatitis B virus) inhibitor (antagonist) with EC50 of 10 μM. |
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V54210 | HBV-IN-38 | 1834483-86-1 | HBV (hepatitis B virus)-IN-38 (Example 193) is an HBV (hepatitis B virus) DNA inhibitor (EC50≤100nM). |
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V54200 | HBV-IN-39-d3 | 2173356-23-3 | HBV (hepatitis B virus)-IN-39-d3 (Example 14) is a deuterated form of HBV (hepatitis B virus)-IN-39 (Example 13). |
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V78340 | HBV-IN-40 | HBV (hepatitis B virus)-IN-40 (Compound 11826096) is an HBV (hepatitis B virus) inhibitor (IC50= 0.7 μM). | |
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V54183 | HBV-IN-41 | 1967002-25-0 | HBV (hepatitis B virus)-IN-41 (compound 45) is a potent orally bioactive HBV (hepatitis B virus) inhibitor (antagonist) with EC50 of 0.027μM. |
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V85418 | HBV-IN-43 | 2305897-05-4 | |
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V88257 | HBV-IN-44 | HBV-IN-44 (Compound (S)-2a) is a HBV inhibitor with an IC50 of 23 nM for HBsAg. | |
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V88252 | HBV-IN-45 | HBV-IN-45 is a selective and orally active HBV capsid assembly modulator with an IC50 of 0.51 μM for HBcAg in HBC cells. | |
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V101156 | HBV-IN-46 | 3034992-40-7 | HBV-IN-46 (Compound 1.6) is an active metabolite. |
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V99639 | HBV-IN-47 | HBV-IN-47 (compound 4a) is a capsid assembly regulator with inhibitory activity against hepatitis B virus (HBV). | |
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V96795 | HBV-IN-49 | 380458-45-7 | HBV-IN-49 is an anti-hepatitis B virus (HBV) drug that inhibits HBV replication. |
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V54197 | HBV-IN-6 | 2724224-47-7 | HBV (hepatitis B virus)-IN-6 is a potent HBV (hepatitis B virus) inhibitor (antagonist) with EC50 of 44 nM. |
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V54185 | HBV-IN-7 | 2724224-49-9 | HBV (hepatitis B virus)-IN-6 is a potent HBV (hepatitis B virus) inhibitor (antagonist) with EC50 of 5 nM. |
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V54175 | HBV-IN-8 | 2724224-57-9 | HBV (hepatitis B virus)-IN-6 is a potent HBV (hepatitis B virus) inhibitor (antagonist) with EC50 of 287.9 nM. |