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HBV

HBV

Hepatitis B virus, also known as HBV or Orthohepadnavirus, is a type of virus that belongs to the Hepadnaviridae family of viruses. Hepatitis B is brought on by the virus HBV. The ground squirrel hepatitis virus, the woodchuck hepatitis virus, and the woolly monkey hepatitis B virus are the other three species that make up the Orthohepadnavirus, of which the hepatitis B virus is the type species. The Hepadnaviridae family includes the genus as a member. Based on antigenic epitopes found on its envelope proteins, HBV is classified into four major serotypes (adr, adw, ayr, ayw), and eight genotypes (A-H) based on the genome's overall nucleotide sequence variation.The genotypes are used to track the evolution and spread of the virus because they have a distinct geographic distribution. The severity of the disease, the progression and propensity for complications, the response to treatment, and perhaps vaccination, are all impacted by genotype differences.

HBV related products

Structure Cat No. Product Name CAS No. Product Description
Lagociclovir valactate V54201 Lagociclovir valactate 1001670-19-4 Lagociclovir valactate is the prodrug of Lagociclovir.
Lenvervimab (GC1102) V51872 Lenvervimab (GC1102) 2055006-79-4 Lenvervimab (GC1102) is an IgG1 recombinant human hepatitis B immunoglobulin.
Libivirumab (17.1.41) V51860 Libivirumab (17.1.41) 569658-79-3 Libivirumab (17.1.41) is a humanized anti-HBV (hepatitis B virus) monoclonal antibody (mAb).
LPRP-Et-97543 V51847 LPRP-Et-97543 84638-48-2 LPRP-Et-97543 is a potent anti-HBV (hepatitis B virus) active molecule.
Morphothiadin (GLS4) V5190 Morphothiadin (GLS4) 1092970-12-1 Morphothiadin (formerly GLS-4; GLS4) is a novel, potent and selective inhibitor of HBV replication, effective against both wild-type and adefovir-resistant HBV with an IC50of 12 nM.
Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) V54180 Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) 123410-65-1 Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) is an HBV (hepatitis B virus) inhibitor.
Neracorvir V54187 Neracorvir 2243162-66-3 Neracorvir is a potent antiviral compound.
NVR 3-778 V25189 NVR 3-778 1445790-55-5 NVR 3-778 is a first-in-class, potent and oral bioavailable capsid assembly modulator against the hepatitis B virus [HBV CAM].
Oleana-2,12-dien-28-oic acid V41067 Oleana-2,12-dien-28-oic acid 272108-04-0 Oleana-2,12-dien-28-oic acid is an HBV (hepatitis B virus)-DNA inhibitor, HBsAg and HBeAg inhibitor.
Oxynitidine V54178 Oxynitidine 548-31-2 Oxynitidine is an HBV (hepatitis B virus) inhibitor (ID50=30.8 µg/mL), which can effectively inhibit the DNA replication activity of HBV (hepatitis B virus).
Periglaucine B ((+)-Periglaucine B) V54203 Periglaucine B ((+)-Periglaucine B) 1025023-05-5 Periglaucine B ((+)-Periglaucine B) is an alkaloid and HBsAg inhibitor.
Picroside IV (胡黄连苷IV) V54181 Picroside IV (Picroside IV) 211567-04-3 Picroside IV is an iridoid glycoside derived from the underground parts of Coptidis rhizome.
RG7834 S-isomer V3656 RG7834 S-isomer 2072057-17-9 RG7834 S-isomer, also known asRO 7020322 is the S-enantiomer of RG7834 (RO-7020322) which is a novel, potent and orally bioavailable inhibitor of HBV viral gene expression which blocks viral antigen and virion production.
RO6889678 V7268 RO6889678 1578153-27-1 RO6889678 (RO-6889678) is a novel and potent inhibitor of HBV, inhibitingHBV capsid formation.
Sanggenol P (桑根酮醇P) V54182 Sanggenol P 1351931-30-0 Sanggenol P is a flavonoid that has anti-HBV (hepatitis B virus) activity against HepG2.2.15 cell line in vitro.
Schisanwilsonin C (Arisanschinin K) V54198 Schisanwilsonin C (Arisanschinin K) 1181216-83-0 Schisanwilsonin C (Arisanschinin K) has anti-HBV (hepatitis B virus) activity.
Sophoranol (槐醇) V35025 Sophoranol (Sophoranol) 3411-37-8 Sophoranol is an alkaloid extracted from S. flavescens and has antiviral effect.
Tiviciclovir (AM188) V54207 Tiviciclovir (AM188) 103024-93-7 Tiviciclovir (AM188) is an antiviral guanosine analog and a hepatitis B virus inhibitor.
Tiviciclovir hydrochloride (AM188 hydrochloride) V84061 Tiviciclovir hydrochloride (AM188 hydrochloride)
TLR8 agonist 4 V54184 TLR8 agonist 4 2761697-69-0 TLR8 agonist 4 displays potent inhibitory effects on both wild-type and drug-resistant (lamivudine and entecavir) HBV (hepatitis B virus) strains.
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