Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V72214 | p,p'-DDD-d8 (4,4'-DDD-d8; p,p'-Dichlorodiphenyl dichloroethane-d8) | 93952-20-6 | p,p'-DDD-d8 is the deuterium labelled form of p,p'-DDD. |
|
V67618 | p,p'-DDE-d8 (4,4'-DDE-d8; p,p'-Dichlorodiphenyldichloroethylene-d8) | 93952-19-3 | p,p'-DDE-d8 is the deuterated form of p,p'-DDE. |
|
V72122 | Paeoniflorgenin (paeoniflorgenin) | 697300-41-7 | Paeoniflorgenin is the deglycosylated metabolite of Paeoniflorin. |
|
V72242 | Perindopril acyl-β-D-glucuronide | 120398-66-5 | Perindopril acyl-β-D-glucuronide is a metabolite of Perindopril. |
|
V72287 | Perphenazine sulfoxide | 10078-25-8 | Perphenazine sulfoxide is the sulfoxide metabolite of Perphenazine, formed by the oxidation of Perphenazine. |
|
V72163 | Pseudoerythromycin A enol ether (LY267108) | 105882-69-7 | Pseudoerythromycin A enol ether (LY267108) is a degradation product of erythromycin. |
|
V72151 | Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide) | 38934-20-2 | Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a metabolite of Quercetin, can be extracted from the Uncarina species in Madagascar. |
|
V72146 | Quetiapine sulfoxide hydrochloride (quetiapine sulfoxide hydrochloride; Quetiapine S-oxide hydrochloride) | 2448341-72-6 | Quetiapine sulfoxide HCl (Quetiapine S-oxide HCl) is the major metabolite of Quetiapinem. |
|
V72248 | Radafaxine ((S,S)-Hydroxybupropion; GW-353162A free base; BW-306U free base) | 192374-14-4 | Radafaxine ((S,S)-Hydroxybupropion) is an antidepressant compound. |
|
V70587 | Ramelteon metabolite M-II-d3 | 1246812-22-5 | Ramelteon metabolite M-II-d3 is the deuterium labelled form of Ramelteon metabolite M-II. |
|
V69537 | Regorarafénib N-oxyde-d3(M2) (Regorafénib N-oxide (M2 metabolite) impurity 13-d3) | 1333489-03-4 | Regorafénib N-oxyde-d3(M2) is the deuterated form of Regorafénib N-oxyde M2. |
|
V72175 | Resveratrol-3-O-sulfate sodium | 858127-11-4 | Resveratrol-3-O-sulfate (sodium) is a metabolite of Resveratrol. |
|
V72276 | Ritalinic acid (Ritalinic acid; Ritalinate) | 19395-41-6 | Ritalinic acid (Ritalinate) is the major inactive urinary metabolite of Methylphenidate. |
|
V72213 | Rosuvastatin lactone | 503610-43-3 | Rosuvastatin lactone is a metabolite of rosuvastatin, an HMG-CoA inhibitor. |
|
V72157 | RP101075 | 1306760-73-5 | RP101075, the bioactive metabolite of Ozanimod, is a potent oral S1PR1 agonist/activator with EC50 of 0.27 nM. |
|
V72241 | RP101442 | 1306761-08-9 | RP101442, the bioactive metabolite of Ozanimod, is a selective S1PR1 agonist/activator with EC50s of 2.6 nM and 171 nM for S1PR1 and S1PR5, respectively. |
|
V76549 | RP101988 | RP101442 is the main bioactive metabolite of Ozanimod and a selective S1PR1 agonist/activator with EC50s of 0.19 nM and 32.8 nM for S1PR1 and S1P5R respectively. | |
|
V76548 | RPR132595A hydrochloride (NPC hydrochloride) | RPR132595A (NPC) HCl is the bioactive metabolite of CPT-11, which is produced by cytochrome P-450 3A4 (CYP3A4) and is ultimately excreted in the urine. | |
|
V72172 | S-Allylmercapturic acid | 23127-41-5 | S-Allylmercapturic acid is a biomarker of garlic consumption food intake (BFI). |
|
V72298 | Seco Rapamycin (Secorapamycin; Secorapamycin A) | 147438-27-5 | Seco Rapamycin (Secorapamycin A) is the open-ring metabolite of Rapamycin. |
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