Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.
Structure | Cat No. | Product Name | CAS No. | Product Description |
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V72196 | α-Demethylnaproxen | 23981-47-7 | α-Demethylnaproxen is the major metabolite of Nabumetone , an orally bioactive COX-2 inhibitor (antagonist) with anti~inflammatory activity. |
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V72246 | β-Nicotyrine | 487-19-4 | β-Nicotyrine is a metabolite of Nicotine. |
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V72143 | ω-Hydroxy-DEET | 72236-22-7 | ω-Hydroxy-DEET is a major metabolite of the insect repellent DEET. |