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Drug Metabolite

Drug Metabolite

Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite. 

Drug Metabolite related products

Structure Cat No. Product Name CAS No. Product Description
3'-Hydroxy Repaglinide-d5 V72135 3'-Hydroxy Repaglinide-d5 1352792-15-4 3'-Hydroxy Repaglinide-d5 is the deuterium labelled form of 3'-Hydroxy Repaglinide.
3,4,5-Trimethoxyphenylacetic acid V72134 3,4,5-Trimethoxyphenylacetic acid 951-82-6 3,4,5-Trimethoxyphenylacetic acid is a metabolite of Mescaline.
3,4-Dehydro Cilostazol (OPC-13015) V72120 3,4-Dehydro Cilostazol (OPC-13015) 73963-62-9 3,4-Dehydro Cilostazol (OPC-13015) is the bioactive metabolite of cilostazol (CLZ).
3-(1-Nitrosopyrrolidin-2-yl)pyridine V72232 3-(1-Nitrosopyrrolidin-2-yl)pyridine 80508-23-2 3-(1-Nitrosopyrrolidin-2-yl)pyridine is a major tobacco-specific nitrosamine.
3-Amino-2-oxazolidinone (AOZ) V72118 3-Amino-2-oxazolidinone (AOZ) 80-65-9 3-Amino-2-oxazolidinone (AOZ) is the metabolite of furazolidinone.
3-Hydroxycarbofuran (3-Hydroxycarbofuran) V71650 3-Hydroxycarbofuran (3-Hydroxycarbofuran) 16655-82-6 3-Hydroxycarbofuran is the major metabolite of Carbofuran and is a reversible inhibitor of acetylcholinesterase (AChE).
3-Hydroxyphenazepam V72211 3-Hydroxyphenazepam 70030-11-4 3-Hydroxyphenazepam is the bioactive metabolite of Cinazepam.
3-Methyl-2-quinoxalinecarboxylic acid (MQCA) V72171 3-Methyl-2-quinoxalinecarboxylic acid (MQCA) 74003-63-7 3-Methyl-2-quinoxalinecarboxylic acid (MQCA) is an important N-oxide reducing metabolite of Quinocetone or Olaquindox, which can effectively suppress the growth of Zhang's hepatocytes through S-phase cell cycle arrest.
3-O-Methyl-6β-naltrexone V72160 3-O-Methyl-6β-naltrexone 65150-66-5 3-O-Methyl-6β-naltrexone is a metabolite of naltrexone.
4′-Dihydrophaseic acid V72256 4′-Dihydrophaseic acid 41756-77-8 4′-Dihydrophaseic acid is an abscisic acid metabolite.
4'-Hydroxy diclofenac-13C6 (4'-Hydroxydiclofenac-13C6) V72235 4'-Hydroxy diclofenac-13C6 (4'-Hydroxydiclofenac-13C6) 1189656-64-1 4'-Hydroxy diclofenac-13C6 is 13C (carbon 13)-labeled 4'-Hydroxy diclofenac.
4'-Hydroxy diclofenac-d4 V72115 4'-Hydroxy diclofenac-d4 254762-27-1 4'-Hydroxy diclofenac-d4 is the deuterated form of 4'-Hydroxy diclofenac.
4'-Hydroxydiclofenac V9099 4'-Hydroxydiclofenac 64118-84-9 4'-Hydroxydiclofenac is an active CYP2C9-mediated metabolite of diclofenac which is potent nonsteroidal anti-inflammatory drug (NSAID) anda Cox-2 inhibitor.
4'-Hydroxytamoxifen V67688 4'-Hydroxytamoxifen 82413-23-8 4'-Hydroxytamoxifen is a metabolite of Tamoxifen.
4-Desmethyl Istradefylline V40039 4-Desmethyl Istradefylline 160434-48-0 4-Desmethyl Istradefylline is the demethylated metabolite of Istradefylline (KW-6002; Nourianz), which is an orally bioavailable adenosine A2A receptor (A2AR) antagonist approved for the treatment of PD (Parkinson's disease).
4-Epioxytetracycline V72136 4-Epioxytetracycline 14206-58-7 4-Epioxytetracycline is a degradation product of Oxytetracycline and is found in pig manure compost and wastewater.
4-Hydroxy Atorvastatin lactone (P-Hydroxyatorvastatin lactone; 4-ATL) V72263 4-Hydroxy Atorvastatin lactone (P-Hydroxyatorvastatin lactone; 4-ATL) 163217-70-7 4-Hydroxy Atorvastatin lactone is the metabolite of Atorvastatin.
4-Hydroxy xylazine (Xylazine Impurity 10) V84042 4-Hydroxy xylazine (Xylazine Impurity 10) 145356-32-7
4-Hydroxy-3-methoxyamphetamine hydrochloride V72203 4-Hydroxy-3-methoxyamphetamine hydrochloride 13062-61-8 4-Hydroxy-3-methoxyamphetamine HCl is a metabolite of 3,4-methylenedioxymethamphetamine (MDMA).
4-Hydroxylidocaine V72231 4-Hydroxylidocaine 39942-41-1 4-Hydroxylidocaine is a metabolite of Lidocaine.
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