Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V29894 | 4-Hydroxymephenytoin | 61837-65-8 | 4-Hydroxymephenytoin is a metabolite of the antiepileptic agent mephenytoin; mephenytoin is a ligand of CYP2C19. |
|
V72109 | 4-Hydroxymephenytoin-d3 (hydroxycoumarin-d3) | 1173022-56-4 | 4-Hydroxymephenytoin-d3 is the deuterated form of 4-Hydroxymephenytoin. |
|
V70292 | 4-Hydroxymidazolam | 59468-85-8 | 4-Hydroxymidazolam is a major metabolite of Midazolam. |
|
V72177 | 4-Hydroxyphenylbutazone | 16860-43-8 | 4-Hydroxyphenylbutazone is a metabolite of Phenylbutazone. |
![4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid (2-(4'-trifluoromethylphenyl)-4-methylthiazole-5-carboxylic acid)](http://www.invivochem.com/upload/1124/V72205.png)
|
V72205 | 4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid (2-(4'-trifluoromethylphenyl)-4-methylthiazole-5-carboxylic acid) | 144059-86-9 | 4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid is a metabolite of GW 501516. |
|
V72289 | 5,6-Dihydroabiraterone | 219843-75-1 | 5,6-Dihydroabiraterone is the metabolite of Abiraterone. |
|
V72223 | 5-(3-hydroxyphenyl)-5-phenylhydantoin | 30074-03-4 | 5-(3-hydroxyphenyl)-5-phenylhydantoin is a metabolite of the anti-epileptic active molecule phenytoin. |
|
V72207 | 5-Hydroxythiabendazole (5-OHTBZ) | 948-71-0 | 5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole exposure. |
|
V72216 | 5-NH2-Baicalein | 2478604-99-6 | 5-NH2-Baicalein is an aminated metabolite of Baicalein. |
|
V72127 | 5β-Dihydrocortisol | 1482-50-4 | 5β-Dihydrocortisol, a metabolite of hydrocortisone (Cortisol), is a potential mineralocorticoid. |
|
V79662 | 5β-Dihydrocortisol-d6 | 5β-Dihydrocortisol-d6 is the deuterated form of 5β-Dihydrocortisol. | |
|
V72142 | 6-Azathymine acid | 13924-15-7 | 6-Azathymine acid is a metabolite of Pymetrozine. |
|
V72209 | 6-Hydroxy Chlorzoxazone | 1750-45-4 | 6-Hydroxy Chlorzoxazone is a metabolite of Chlorzoxazone, a centrally acting muscle relaxant used to study muscle spasms. |
|
V50902 | 6α-Hydroxy paclitaxel | 153212-75-0 | 6α-Hydroxypaclitaxel is the primary helper of paclitaxel. |
|
V69913 | 6β-Naltrexol (6β-Hydroxynaltrexone) | 49625-89-0 | 6β-Naltrexol (6β-Hydroxynaltrexone) is the major metabolite of Naltrexone and is a peripherally selective opioid antagonist. |
|
V72210 | 7-Hydroxymethotrexate-d3 (7-Hydroxymethotrexate-d3) | 432545-62-5 | 7-Hydroxymethotrexate-d3 is the deuterated marker of 7-Hydroxymethotrexate, the major metabolite of Methotrexate (MTX). |
|
V79850 | 7-Hydroxymethotrexate-d3 ammonium (7-Hydroxymethotrexate-d3) | 7-Hydroxymethotrexate-d3 (ammonium) is the deuterated marker of 7-Hydroxymethotrexate ammonium, the major metabolite of Methotrexate (MTX). | |
|
V72200 | 7-Hydroxyquetiapine ( (ICI 214227)) | 139079-39-3 | 7-Hydroxyquetiapine (ICI 214227) is the main active metabolite of the antipsychotic active molecule quetiapine [1]. |
|
V72273 | 8′-HydroxyABA (8′-OH-ABA) | 77209-34-8 | 8′-Hydroxy ABA (8′-OH-ABA) is the main breakdown product of abscisic acid (ABA). |
|
V80170 | 8′-HydroxyABA-d2 (8′-OH-ABA-d2) | 8′-Hydroxy ABA-d2 is the deuterated label of 8′-Hydroxy ABA. |
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