Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V80188 | 8′-HydroxyABA-d8 (8′-OH-ABA-d8) | 8′-Hydroxy ABA-d8 is a deuterated label of 8′-Hydroxy ABA. | |
|
V72195 | 8-Demethyl Ivabradine | 304464-97-9 | 8-Demethyl Ivabradine is a metabolite of Ivabradine. |
|
V71734 | 9-Fluorenol (9-Hydroxyfluorene) | 1689-64-1 | 9-Fluorenol (9-Hydroxyfluorene; compound 3) is a DAT (dopamine) inhibitor (antagonist) with IC50 of 9 μM. |
|
V72185 | Abiraterone N-oxide | 2378463-76-2 | Abiraterone N-oxide is the metabolite of Abiraterone. |
|
V72132 | Abiraterone sulfate | 1993430-25-3 | Abiraterone sulfate is the metabolite of Abiraterone. |
|
V30699 | Acetaminophen metabolite 3-hydroxy-acetaminophen | 37519-14-5 | 3-hydroxy-acetaminophen is a metabolite of Acetaminophen. |
|
V77781 | ACT-606559 | ACT-606559 is a new compound with antimalarial activity and is a metabolite of ACT451840. | |
|
V72186 | Afatinib N-Oxide | 2413212-11-8 | Afatinib N-Oxide is an impurity during the oxidative degradation of Afatinib dimaleate. |
|
V72165 | Ampyrone-d3 (4-Aminoantipyrine-d3) | 1329792-51-9 | Ampyrone-d3 is the deuterated form of Ampyrone. |
|
V72150 | Apalutamide-COOH | 1332391-04-4 | Apalutamide-COOH is the metabolite of Apalutamide. |
|
V72145 | Apovincaminic acid hydrochloride salt | 72296-47-0 | Apovincaminic acid HCl salt is an orally bioactive and BBB (blood-brain barrier) permeable (penetrable) major bioactive metabolite of Vinpocetine (VP). |
|
V72108 | AR-13503 (AR-13324 M1 metabolite) | 2309668-15-1 | AR-13503 (AR-13324 M1 metabolite) is the hydrolysis metabolite of AR-13324 mesylate. |
|
V69342 | AST5902 trimesylate | 2929417-90-1 | AST5902 trimesylate is the major metabolite of Alflutinib (AST2818) in vivo and in vitro. |
|
V72173 | Aszonalenin | 81797-27-5 | Aszonalenin is a metabolite of Aspergillus zonatus. |
|
V38962 | Atorvastatin Epoxy Tetrahydrofuran Impurity | 873950-19-7 | Atorvastatin Epoxy Tetrahydrofuran Impurity is an oxidative degradation product of Atorvastatin,which is an anti-hyperlipidemic drug and selectiveinhibitor of HMG-CoA reductase. |
|
V69365 | AZ7550-d5 | 2719690-99-8 | AZ7550-d5 is the deuterium labelled form of AZ7550. |
|
V32638 | Berberrubine chloride | 15401-69-1 | Berberrubine chloride, a potent metabolite of berberine, reduces symptoms of ulcerative colitis in animal models. |
|
V72270 | Bifenazate-diazene | 149878-40-0 | Bifenazate-diazene is the main degradation product of Bifenazate. |
|
V72290 | Captopril EP Impurity B (Captopril EP Impurity B) | 80629-35-2 | Captopril EP Impurity B is an impurity of Captopril. |
|
V72291 | Captopril EP Impurity C (3-Mercaptoisobutyric acid; 3-Mercaptoisobutyric acid) | 26473-47-2 | Captopril EP Impurity C is an impurity of Captopril. |
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