Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V72162 | Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside; Deoxynivalenol 3-glucoside) | 131180-21-7 | Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a metabolite of the fusarium toxin deoxynivalenol. |
|
V19605 | Des(benzylpyridyl) Atazanavir | 1192224-24-0 | Des(benzylpyridyl) Atazanavir (compound M1) is an N-dealkylated Atazanavir metabolite. |
|
V72124 | Desmethyl Erlotinib (Desmethyl Erlotinib; OSI-420 free base; CP-373420) | 183321-86-0 | Desmethyl Erlotinib (OSI-420 free base) is the bioactive metabolite of Erlotinib, an EGFR tyrosine kinase inhibitor. |
|
V72275 | Desoxycarbadox | 55456-55-8 | Desoxycarbadox is a metabolite of Carbadox. |
|
V71231 | Desvenlafaxine fumarate (O-Desmethylvenlafaxine fumarate) | 93414-04-1 | Desvenlafaxine (O-Desmethylvenlafaxine) fumarate is a selective serotonin and norepinephrine reuptake inhibitor. |
|
V72148 | Devaleryl Valsartan Impurity (Valsartan Impurity Valsartan Desvaleryl Impurity) | 676129-92-3 | Devaleryl Valsartan Impurity is an intermediate in the preparation /synthesis of Valsartan. |
|
V72187 | Didesmethylsibutramine hydrochloride (BTS 54-505) | 84484-78-6 | Didesmethylsibutramine (BTS 54-505) HCl is the primary amine metabolite of Sibutramine, an antidepressant and anti-obesity compound. |
|
V40044 | Dihydro Dutasteride | 164656-22-8 | Dihydro Dutasteride is an impurity generated during the production of Dutasteride (GI198745, GG745; GI-198745, GG-745;Avodart, Avidart), which is an approved anticancer medication and a 5-α reductase inhibitor. |
|
V72238 | DM-CO-(CH2)5-SMe | 2243689-84-9 | DM-CO-(CH2)5-SMe is an anticancer agent derived from antibody active molecular conjugate (ADC) metabolites and is cytotoxic to H1703, H1975, COLO704 and Colo720E cells. |
|
V72201 | Doxorubicinol hydrochloride (13-Dihydroadriamycin hydrochloride) | 63950-05-0 | Doxorubicinol HCl (13-Dihydroadriamycin HCl) is the secondary alcohol metabolite of Doxorubicin. |
|
V72261 | DP-1 | 1472616-61-7 | DP-1 is a degradation product of SDC-TRAP-0063 and a fragment of Ganetespib. |
|
V28672 | Duloxetine metabolite Para-Naphthol Duloxetine | 949095-98-1 | Duloxetine metabolite Para-Naphthol Duloxetine is a metabolite of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor (SNRI)used for the treatment of major depressive disorder and generalized anxietydisorder (GAD),fibromyalgia and neuropathic pain. |
|
V83617 | EDDP perchlorate | 31161-17-8 | |
|
V40059 | ent-Ezetimibe | 1376614-99-1 | ent-Ezetimibe is the RRS-enantiomer and impurity of Ezetimibe (SCH-58235), which is a selective inhibitor of cholesterol absorption in the gut used to lower cholesterol levels. |
|
V40125 | Enzalutamide carboxylic acid | 1242137-15-0 | Enzalutamide carboxylic acid(also called MDV-3100 carboxylic acid)is a major inactive metabolite of Enzalutamide (MDV3100; Xtandi) which is a non-steroidal androgen-receptor (AR) antagonist approved for use as an anticancer drug. |
|
V72257 | Ezetimibe hydroxy glucuronide (SCH 488128; Ezetimibe hydroxy β-D-Glucuronide) | 536709-33-8 | Ezetimibe hydroxy glucuronide (SCH 488128) is a trace metabolite detected in dog and human plasma samples after oral administration of Ezetimibe. |
|
V40057 | Ezetimibe phenoxy glucuronide | 190448-57-8 | Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the bioactive metabolite of Ezetimibe and has anti-hyperlipoproteinemia effects. |
|
V72184 | Ezetimibe phenoxy glucuronide-d4-1 (Ezetimibe phenoxy glucuronide-d4) | 2798007-90-4 | Ezetimibe phenoxy glucuronide-d4-1 is a deuterium labelled Ezetimibe phenoxy glucuronide. |
|
V71982 | Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) | 1351692-92-6 | Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) is a metabolite of Febuxostat. |
|
V72280 | Febuxostat amide impurity (Febuxostat Impurity 4) | 1239233-86-3 | Febuxostat amide impurity is an impurity in Febuxostat. |
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