Glycoside hydrolase enzymes are glucosidases. A glucosidase that works on α(1→4) bonds is called α-glucosidase, and it is found in the small intestine's brush border. α-Glucosidase inhibitors are a new class of diabetes medications. It can effectively control blood sugar levels and prevent diabetic complications by lowering the postprandial blood sugar concentration.
In β-D-glucosides and oligosaccharides, β-glucosidase catalyzes the hydrolysis of the glycosidic bonds to terminal non-reducing residues, releasing glucose in the process. Because of its crucial function in the breakdown of cellulose, the transformation of glycosides, and numerous other industrial processes, β-glucosidase has garnered a great deal of interest from the scientific community. In order to degrade cellulose, β-glucosidases are crucial because they catalyze the last stage of cellulose hydrolysis.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V88493 | MPO-IN-7 | MPO-IN-7 (compound MDC) is a myeloperoxidase inhibitor with IC50 values of 41 μM, 25 μM and 4.5 μM for α-glucosidase, dipeptidyl peptidase-4 and myeloperoxidase, respectively. | |
|
V87305 | Sekikaic acid | 607-11-4 | Sekikaic acid is an inhibitor of α-glucosidase and α-amylase, with hypolipidemic, antioxidant and antidiabetic activities. |
|
V84927 | Tachioside | 109194-60-7 | |
|
V87198 | α-Amylase/α-Glucosidase-IN-10 | α-Amylase/α-Glucosidase-IN-10 (compound 5d) is an inhibitor of α-amylase and α-glucosidase (IC50: 30.39 μM and 65.1 μM), with potential inhibitory effects on diabetes. | |
|
V87300 | α-Amylase/α-Glucosidase-IN-11 | α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is an isoxazolidine-indigo hybrid with significant antidiabetic activity. | |
|
V87301 | α-Amylase/α-Glucosidase-IN-12 | α-Amylase/α-Glucosidase-IN-12 (compound 10k) is a dual inhibitor targeting α-glucosidase and α-amylase with IC50 of 34.52 nM and 24.62 nM, respectively. | |
|
V87303 | α-Amylase/α-Glucosidase-IN-13 | α-Amylase/α-Glucosidase-IN-13 (Compound 5d) is a dual inhibitor of α-Amylase/α-Glucosidase, which can be used in the research of diabetes. | |
|
V87310 | α-Amylase/α-Glucosidase-IN-14 | α-Amylase/α-Glucosidase-IN-14 is an orally bioavailable α-amylase and α-glucosidase inhibitor with IC50 of 45.53 μM and 27.73 μM, respectively. | |
|
V87304 | α-Amylase/α-Glucosidase-IN-15 | α-Amylase/α-Glucosidase-IN-15 (compound 6C) is an orally active inhibitor of α-glucosidase (α-Glucosidase) and α-amylase (α-amylase) with IC50 of 21 μM and 61 μM, respectively. | |
|
V87302 | α-Amylase/α-Glucosidase-IN-16 | α-Amylase/α-Glucosidase-IN-16 (compound 15) is a potent dual inhibitor of α-amylase and α-glucosidase with IC50 values of 0.8 and 1.2 μM, respectively. | |
|
V85826 | α-Amylase/α-Glucosidase-IN-7 | 1038094-94-8 | |
|
V84365 | α-Amylase/α-Glucosidase-IN-8 | ||
|
V87298 | α-Amylase/α-Glucosidase-IN-9 | α-Amylase/α-Glucosidase-IN-9 (compound 5h) is a dual inhibitor of α-amylase (IC50 = 16.4 μM) and α-glucosidase (IC50 = 31.6 μM). | |
|
V85992 | α-Glucosidase-IN-44 | ||
|
V85880 | α-Glucosidase-IN-45 | 3026192-46-8 | |
|
V84859 | α-Glucosidase-IN-46 | ||
|
V85169 | α-Glucosidase-IN-47 | ||
|
V87452 | α-Glucosidase-IN-48 | α-Glucosidase-IN-48 (compound 9) is a potent inhibitor of α-Glucosidase with IC50 of 1.30 μM. | |
|
V83417 | α-Glucosidase-IN-49 | ||
|
V87468 | α-Glucosidase-IN-50 | α-Glucosidase-IN-50 (compound 8) is an inhibitor of α-Glucosidase. |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
