Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.
Structure | Cat No. | Product Name | CAS No. | Product Description |
---|---|---|---|---|
V74062 | 306-O12B | 2566523-06-4 | 306-O12B is an ionizable cationic lipid used to generate lipid nanoparticles (LNPs). | |
V83466 | 306-O12B-3 | |||
V74059 | 306Oi10 | 2322290-93-5 | 306Oi10 is a branched-chain ionizable liposome that may be utilized to construct lipid nanoparticles (LNPs) for the delivery of messenger RNA. | |
V73445 | 4A3-Cit | 2768211-13-6 | 4A3-Cit is an ionizable lipid used to generate lipid nanoparticles (LNPs). | |
V73471 | 50-C2-C9-4tail | 1853203-01-6 | 50-C2-C9-4tail has been used to prepare lipid nanoparticles (LNPs) for delivery of siRNA and mRNA in vitro & in vivo. | |
V73490 | 6-Bromohexyl 2-hexyldecanoate | 2644752-91-8 | 6-Bromohexyl 2-hexyldecanoate is a lipid. | |
V73467 | 7-Oxotridecanedioic acid | 101171-43-1 | 7-Oxotridecanedioic acid is a degradable cationic lipid intermediate compound used in the formation of lipid nanoparticles. | |
V73409 | 80-O14B | 1624618-01-4 | 80-O14B is a cationic lipid-like compound for CRISPR/Cas9 delivery. | |
V83364 | 93-O17O | 2227214-78-8 | ||
V74083 | 93-O17S | 2227008-67-3 | 93-O17S is a cationic lipid used to prepare lipid nanoparticles (LNPs). | |
V73444 | A12-Iso5-4DC19 | 2412492-20-5 | A12-Iso5-4DC19 is an ionizable cationic lipid. | |
V60073 | A18-Iso5-2DC18 | 2412492-09-0 | A18-Iso5-2DC18 (compound A18) is a cyclic ionizable cationic lipid that promotes mRNA protein expression and induces strong mediated immune responses. | |
V73453 | A2-Iso5-4DC19 | 2412492-19-2 | A2-Iso5-4DC19 is a lipid compound. | |
V74073 | AA-T3A-C12 | 2938207-23-7 | AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid). | |
V41502 | ALC-0159 | 1849616-42-7 | ALC-0159 (ALC0159; ALC 0159) is PEGylated lipid (PEG/lipid conjugate) and non-ionic surfactant usedin thePfizer-BioNTechSARS-CoV-2(COVID-19) mRNA vaccine containing the active ingredienttozinameran. | |
V2455 | ALC-0315 | 2036272-55-4 | ALC-0315 (ALC0315;ALC 0315) is a synthetic, colorless oily cationic lipid and an ionizable amino lipid used in combination with other lipids in the formation of lipid nanoparticles (LNPs) as non-viral gene delivery system. | |
V73434 | ALC-0315 analogue-1 | 2707440-55-7 | ALC-0315 analog-1 (compound P-10) is a cationic lipid. | |
V73418 | ALC-0315 analogue-2 | 2707439-64-1 | ALC-0315 analogue-2 is an analogue of ALC-0315. | |
V74049 | ApoA-I mimetic peptide | 221882-20-8 | ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyltransferase (LCAT) activating effect. | |
V83421 | ATX-001 | 1777792-33-2 |