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Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
306-O12B V74062 306-O12B 2566523-06-4 306-O12B is an ionizable cationic lipid used to generate lipid nanoparticles (LNPs).
306-O12B-3 V83466 306-O12B-3
306Oi10 V74059 306Oi10 2322290-93-5 306Oi10 is a branched-chain ionizable liposome that may be utilized to construct lipid nanoparticles (LNPs) for the delivery of messenger RNA.
4A3-Cit V73445 4A3-Cit 2768211-13-6 4A3-Cit is an ionizable lipid used to generate lipid nanoparticles (LNPs).
50-C2-C9-4tail V73471 50-C2-C9-4tail 1853203-01-6 50-C2-C9-4tail has been used to prepare lipid nanoparticles (LNPs) for delivery of siRNA and mRNA in vitro & in vivo.
6-Bromohexyl 2-hexyldecanoate V73490 6-Bromohexyl 2-hexyldecanoate 2644752-91-8 6-Bromohexyl 2-hexyldecanoate is a lipid.
7-Oxotridecanedioic acid V73467 7-Oxotridecanedioic acid 101171-43-1 7-Oxotridecanedioic acid is a degradable cationic lipid intermediate compound used in the formation of lipid nanoparticles.
80-O14B V73409 80-O14B 1624618-01-4 80-O14B is a cationic lipid-like compound for CRISPR/Cas9 delivery.
93-O17O V83364 93-O17O 2227214-78-8
93-O17S V74083 93-O17S 2227008-67-3 93-O17S is a cationic lipid used to prepare lipid nanoparticles (LNPs).
A12-Iso5-4DC19 V73444 A12-Iso5-4DC19 2412492-20-5 A12-Iso5-4DC19 is an ionizable cationic lipid.
A18-Iso5-2DC18 V60073 A18-Iso5-2DC18 2412492-09-0 A18-Iso5-2DC18 (compound A18) is a cyclic ionizable cationic lipid that promotes mRNA protein expression and induces strong mediated immune responses.
A2-Iso5-4DC19 V73453 A2-Iso5-4DC19 2412492-19-2 A2-Iso5-4DC19 is a lipid compound.
AA-T3A-C12 V74073 AA-T3A-C12 2938207-23-7 AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid).
ALC-0159 V41502 ALC-0159 1849616-42-7 ALC-0159 (ALC0159; ALC 0159) is PEGylated lipid (PEG/lipid conjugate) and non-ionic surfactant usedin thePfizer-BioNTechSARS-CoV-2(COVID-19) mRNA vaccine containing the active ingredienttozinameran.
ALC-0315 V2455 ALC-0315 2036272-55-4 ALC-0315 (ALC0315;ALC 0315) is a synthetic, colorless oily cationic lipid and an ionizable amino lipid used in combination with other lipids in the formation of lipid nanoparticles (LNPs) as non-viral gene delivery system.
ALC-0315 analogue-1 V73434 ALC-0315 analogue-1 2707440-55-7 ALC-0315 analog-1 (compound P-10) is a cationic lipid.
ALC-0315 analogue-2 V73418 ALC-0315 analogue-2 2707439-64-1 ALC-0315 analogue-2 is an analogue of ALC-0315.
ApoA-I mimetic peptide V74049 ApoA-I mimetic peptide 221882-20-8 ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyltransferase (LCAT) activating effect.
ATX-001 V83421 ATX-001 1777792-33-2
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