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Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
ATX-002 V74074 ATX-002 1777792-34-3 ATX-002 is an ionizable cationic lipid for RNA drug delivery.
BAMEA-O16B V60071 BAMEA-O16B 2490668-30-7 BAMEA-O16B is a lipid nanoparticles.
BP Lipid 114 V73421 BP Lipid 114 2714482-25-2 BP Lipid 114 is an ethanolamine ionizable lipid (CN113387825A).
BP Lipid 135 V73463 BP Lipid 135 2089251-35-2 BP Lipid 135 is a cationically ionizable lipid.
C14-4 V74075 C14-4 2639634-80-1 C14-4 is an ionizable lipid used in the preparation /synthesis of lipid nanoparticles.
Cholesterol (Water Soluble) V77149 Cholesterol (Water Soluble) Cholesterol Water Soluble may be utilized to study the effects of cholesterol on potassium currents in inner hair cells.
CL4F8-6 V73486 CL4F8-6 2766493-12-1 CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14.
CRX-547 V50916 CRX-547 216014-05-0 lipid A mimetic
CTP-NBD V82217 CTP-NBD 1268513-27-4 CTP-NBD is a cell-penetrating/penetrable and specific NFκB inhibitor.
D-Lin-MC3-DMA V20104 D-Lin-MC3-DMA 1224606-06-7 D-Lin-MC3-DMA is a potent andionizable / cationic lipid that has been used for synthesis of lipid nanoparticles (LNPs, gene vector) to deliver siRNA.
DGDG V73410 DGDG 63142-69-8 DGDG, a chloroplast lipid, is a bilayer-forming lipid.
di-Pal-MTO V73485 di-Pal-MTO 1349197-90-5 di-Pal-MTO is a palm oil-based lipid produced by combining the anti-cancer active molecule mitoxantrone (MTO) with palmitoleic acid.
Diamino lipid DAL4 V73437 Diamino lipid DAL4 2939000-43-6 Diamino lipid DAL4 is a new type of lipid nanoparticles (LNPs) that can encapsulate mRNA encoding cytokines such as IL-12, IL-27 and GM-CSF.
Dicamba-(CH2)5-acid V82220 Dicamba-(CH2)5-acid 2892008-07-8 Hapten Dca is an immune hapten.
Dielaidoylphosphatidylethanolamine (DEPE) V73476 Dielaidoylphosphatidylethanolamine (DEPE) 16777-83-6 Dielaidoylphosphatidylethanolamine is a liposome used to deliver active molecules.
Dimethyldioctadecylammonium bromide (Dioctadecyldimethylammonium bromide; DODAB) V74064 Dimethyldioctadecylammonium bromide (Dioctadecyldimethylammonium bromide; DODAB) 3700-67-2 Dimethyldioctadecylammonium bromide is a synthetic cationic lipid widely used in gene delivery and vaccine development.
Dios-Arg diTFA V83445 Dios-Arg diTFA 1807353-31-6
DLin-K-C3-DMA V74066 DLin-K-C3-DMA 1217306-46-1 DLin-K-C3-DMA is a cationic lipid that may be utilized in the synthesis/preparation of nucleic acid lipid particles to deliver nucleic acids.
DLin-KC2-DMA V20103 DLin-KC2-DMA 1190197-97-7 DLin-KC2-DMA is novel ionizable and cationic lipid useful for siRNA delivery.
DLin-M-C4-DMA V73439 DLin-M-C4-DMA 1226909-66-5 DLin-M-C4-DMA (Compound MC4) is a cationic lipid.
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