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Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium) V90382 1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium) 326495-23-2 1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (18:0 Lyso PE) sodium is a lysophospholipid containing stearic acid (18:0) at the sn-1 position and can be used in micelles, liposomes, and other types of artificial membranes, including lipid-based drug delivery systems.
1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine V90378 1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine 6418-95-7 1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine, a phospholipid containing stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively, has been used to generate lipid nanoparticles (LNPs) for the delivery of mRNA or nuclear-targeted plasmid DNA in vitro.
1-Thio-β-D-glucose sodium V102654 1-Thio-β-D-glucose sodium 10593-29-0 Sodium 1-thio-β-D-glucose is the sodium salt form of 1-thio-β-D-glucose.
113-N16B V77507 113-N16B 113-N16B is an ionizable cationic lipid that may be utilized to prepare lipid nanoparticles.
16:0 Biotinyl PE V90364 16:0 Biotinyl PE 384835-54-5 16:0 Biotinyl PE is a lipid with a biotin group consisting of one phosphoethanolamine attached to two palmitic acid tails.
16:0 Caproylamine PE V90360 16:0 Caproylamine PE 115288-21-6 16:0 Caproylamine PE is an amino-reactive lipid with one phosphoethanolamine attached to two palmitic acid tails.
16:0 Cardiolipin V93304 16:0 Cardiolipin 105380-95-8 16:0 Cardiolipin (diphosphatidylglycerol (16:0)) is a phospholipid derived from palmitic acid (16:0) that can be used to synthesize lipid nanoparticles (LNPs) for the delivery of mRNA and other payloads.
16:0 Cyanur PE V90365 16:0 Cyanur PE 1246304-37-9 16:0 Cyanur PE is a lipid with a cyanuric acid group and one phosphoethanolamine attached to two palmitic acid tails.
16:0 Glutaryl PE V89601 16:0 Glutaryl PE 474923-45-0 16:0 Glutaryl PE is a carboxylic acid-reactive lipid with one phosphoethanolamine attached to two palmitic acid tails for siRNA delivery.
16:0 MPB PE V89598 16:0 MPB PE 384835-50-1 16:0 MPB PE is a maleimide lipid with one phosphoethanolamine attached to two palmitic acid tails and one phenylmaleimide group.
16:0 PDP PE V90429 16:0 PDP PE 474944-16-6 16:0 PDP PE belongs to a class of head group modified functional lipids.
16:0 PE MCC V90357 16:0 PE MCC 384832-87-5 16:0 PE MCC is a maleimide lipid with one phosphoethanolamine attached to two palmitic acid tails and one maleimide group.
16:0 Succinyl PE V90362 16:0 Succinyl PE 186800-61-3 16:0 Succinyl PE is a lipid with a carboxylic acid reactive group and one phosphoethanolamine attached to two palmitic acid tails.
16:0-23:2 Diyne PC V90356 16:0-23:2 Diyne PC 84271-00-1 16:0-23:2 Diyne PC is a hydrolyzed phosphocholine with palmitic acid (16:0) and pentacosa-10,12-diynoic acid as tails.
16:1 (DELTA 9-Cis) PC (1,2-Dipalmitoleoyl-sn-glycero-3-phosphocholine) V85503 16:1 (DELTA 9-Cis) PC (1,2-Dipalmitoleoyl-sn-glycero-3-phosphocholine) 4724-96-3
17:1 Lyso PC V102420 17:1 Lyso PC 1246304-62-0 17:1 Lyso PC is a liposome that can mimic biological phospholipid membranes.
18:0 DAP V73480 18:0 DAP 121315-93-3 18:0 DAP may be utilized to prepare lipid nanoparticles (LNPs) with mRNA encapsulated in their core.
18:1 Biotinyl Cap PE V87560 18:1 Biotinyl Cap PE 384835-51-2 18:1 Biotinyl Cap PE is a fluorescent lipid with biotin as its head group.
18:1 Biotinyl PE V90363 18:1 Biotinyl PE 384835-53-4 18:1 Biotinyl PE is a lipid with a biotin group with one phosphoethanolamine attached to two oleic acid tails.
18:1 Caproylamine PE V87566 18:1 Caproylamine PE 110796-31-1 18:1 Caproylamine PE is an amino-reactive lipid with one phosphoethanolamine attached to two oleic acid tails.
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