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Liposome

Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.

Liposome related products

Structure Cat No. Product Name CAS No. Product Description
Amino-Gly-Gly-DSPE hydrochloride V90354 Amino-Gly-Gly-DSPE hydrochloride 2446375-49-9 Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used in the synthesis of liposomes.
ApoA-I mimetic peptide V74049 ApoA-I mimetic peptide 221882-20-8 ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyltransferase (LCAT) activating effect.
ATX-001 V83421 ATX-001 1777792-33-2
ATX-002 V74074 ATX-002 1777792-34-3 ATX-002 is an ionizable cationic lipid for RNA drug delivery.
BAMEA-O16B V60071 BAMEA-O16B 2490668-30-7 BAMEA-O16B is a lipid nanoparticles.
BAmP-O16B V97125 BAmP-O16B BAmP-O16B is an ionizable cationic amino lipid that can be used to generate lipid nanoparticles (LNPs).
Biotin-PEGn-NHS ester V101708 Biotin-PEGn-NHS ester 365441-71-0 Biotin-PEGn-NHS ester is a biotin-labeled PROTAC linker that belongs to the PEG class and can be used to synthesize PROTAC molecules.
Bis(2-butyloctyl) 10-oxononadecanedioate V90406 Bis(2-butyloctyl) 10-oxononadecanedioate 2036272-58-7 Bis(2-butyloctyl) 10-oxononadecanedioate is an ionizable lipid containing four hydrophobic tails bound by esters and can be used to prepare liposomes.
Bis(bis(2-carboxyethyl)aminopropyl)methylamine V90431 Bis(bis(2-carboxyethyl)aminopropyl)methylamine 692250-70-7 Bis(bis(2-carboxyethyl)aminopropyl)methylamine is a symmetrical branched linker with three tertiary amines and four carboxylic acids for the development of lipid nanoparticles.
BP Lipid 103 V90408 BP Lipid 103 2714482-36-5 BP Lipid 103 is an ionizable lipid similar to SM-102 and can be used to prepare liposomes or lipid nanoparticles.
BP Lipid 109 V90409 BP Lipid 109 2569015-31-0 BP Lipid 109 is an ionizable lipid with a long (11 carbon) lipid tail on the primary ester, two esters at the C7 position, and an ethanolamine head, which can be used to prepare liposomes or lipid nanoparticles.
BP Lipid 112 V89582 BP Lipid 112 2714482-37-6 BP Lipid 112 is an ionizable lipid with two ester bonds at the C6 and C7 positions.
BP Lipid 113 V90410 BP Lipid 113 2714482-23-0 BP Lipid 113 is an ionizable lipid similar to SM-102 and can be used to prepare liposomes or lipid nanoparticles.
BP Lipid 114 V73421 BP Lipid 114 2714482-25-2 BP Lipid 114 is an ethanolamine ionizable lipid (CN113387825A).
BP Lipid 126 V90413 BP Lipid 126 2157489-64-8 BP Lipid 126 is an ionizable lipid (Compound 143) from patent WO2017201333A1.
BP Lipid 135 V73463 BP Lipid 135 2089251-35-2 BP Lipid 135 is a cationically ionizable lipid.
BP Lipid 142 V90427 BP Lipid 142 2244715-87-3 BP Lipid 142 comes from patent WO2018170306A1 (Compound 261).
BP Lipid 209 V87545 BP Lipid 209 2089251-43-2 BP Lipid 209 is an ionizable lipid that can be used to prepare liposomes or lipid nanoparticles.
BP Lipid 217 V90428 BP Lipid 217 2430034-17-4 BP Lipid 142 is derived from patent WO2023178065A2 (B32).
BP Lipid 218 V90412 BP Lipid 218 2036272-95-2 BP Lipid 218 is an ionizable lipid that can be used to prepare liposomes or lipid nanoparticles.
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