Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. The hydrophobic tails self-orient in aqueous environments, forming a spherical structure with an aqueous core and a lipophilic bilayer membrane surrounding it. Liposomes can be made to be both biocompatible and biodegradable (for instance, at a particular pH and temperature) by changing the lipid composition. Additionally, there are a number of modifications that can be made to liposomes to increase their effectiveness as drug delivery vehicles.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V79572 | Genevant CL1 monohydrochloride | Genevant CL1 mono HCl is an ionizable cationic lipid (lipid 10, pKa=6.3) that can be used for mRNA lipid nanoparticle (LNP) vaccine delivery. | |
|
V76978 | GL67 pentahydrochloride (N4-Spermine cholesteryl carbamate pentahydrochloride) | GL67 (N4-Spermine cholesteryl carbamate) (penta HCl) is a cationic lipid. | |
|
V73419 | Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate | 2714482-26-3 | Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate may be utilized in liposome delivery systems for the delivery of mRNA vaccines. |
|
V74050 | ionizable lipid-1 | 2055939-68-7 | Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that may be utilized to prepare lipid nanoparticles (LNP) with a bilayer structure. |
|
V80392 | Ionizable lipid-1 hydrochloride | Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that may be utilized to prepare lipid nanoparticles (LNP) with a bilayer structure. | |
|
V82218 | Itaconic acid-13C5 (Itaconic acid 13C5) | 2095777-38-9 | Itaconic acid-13C5 is 13C (carbon 13) labelled Itaconic acid. |
|
V60065 | L319 | 1351586-50-9 | L319 also known as O-8670, Lipid 319; RV-92, is an ionizable lipid. |
|
V73420 | Lipid 1 | 2226547-17-5 | Lipid 1 is an ionizable aminolipid that may be utilized to prepare lipid nanoparticles. |
|
V60072 | Lipid 10 | 2430034-02-7 | Lipid 10 is an ionizable aminolipid that may be utilized to prepare lipid nanoparticles. |
|
V74076 | Lipid 14 | 2430034-05-0 | Lipid 14 is an ionizable aminolipid that may be utilized in the preparation /synthesis of lipid nanoparticles (LNPs). |
|
V73455 | Lipid 15 | 2588111-36-6 | Lipid 15 is an ionizable aminolipid that may be utilized to prepare lipid nanoparticles. |
|
V74067 | Lipid 29 | 2244716-55-8 | Lipid 29 is an ionizable aminolipid. |
|
V73450 | Lipid 6 | 2226547-22-2 | Lipid 6 is an ionizable aminolipid that may be utilized to prepare lipid nanoparticles. |
|
V74078 | Lipid 8 | 2226547-25-5 | Lipid 8 is an ionizable aminolipid that may be utilized to prepare lipid nanoparticles. |
|
V60067 | Lipid A9 | 2036272-50-9 | Lipid A9 is an excipient for vaccines. |
|
V85282 | Lipid AX4 | 2735814-23-8 | |
|
V73460 | Lipid C24 | 2767561-52-2 | Lipid C24 is a cationic ionizable lipid that may be utilized in the synthesis/preparation of lipid nanoparticles (LNP). |
|
V73442 | Lipid M | 2089251-57-8 | Lipid M (pKa: 6.75) may be utilized to deliver mRNA vaccines to elicit robust immune responses and improve tolerance. |
|
V73427 | LNP Lipid-1 | 2089253-13-2 | LNP Lipid-1 (Method B) is a lipid compound. |
|
V73440 | LNP Lipid-3 | 2648693-32-5 | LNP Lipid-3 is an ionizable lipid that may be utilized to prepare lipid nanoparticles. |
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